Table 4.
Impact of CALINE4 NOxa on Uterine Artery Resistance
| Visit 1 | Visit 2 | Visit 3 | |||||||
|---|---|---|---|---|---|---|---|---|---|
| n: ≥/ <90th | Model 1b | n: ≥/ <90th | Model 1b | n: ≥/ <90th | Model 1b | ||||
| Pulsatility index | |||||||||
| Per SD (Beta, 95%CI) | 0.03 | -0.07, 0.13 | 0.01 | -0.09, 0.10 | 0.12 | 0.02, 0.23 | |||
| ≥ vs. <90th percentile (Odds ratio, 95% CI) | 56/502 | 1.08 | 0.74, 1.59 | 53/486 | 0.92 | 0.64, 1.32 | 49/437 | 1.17 | 0.79, 1.75 |
| Resistance index | |||||||||
| Per SD (Beta, 95%CI) | 0.04 | -0.06, 0.14 | 0.01 | -0.09, 0.11 | 0.14 | 0.03, 0.24 | |||
| ≥ vs. <90th percentile (Odds ratio, 95% CI) | 56/502 | 1.07 | 0.73, 1.57 | 54/485 | 0.88 | 0.61, 1.25 | 48/438 | 1.17 | 0.78, 1.74 |
| S/D ratio | |||||||||
| Per SD (Beta, 95%CI) | -0.03 | -0.13, 0.07 | -0.00 | -0.10, 0.09 | 0.14 | 0.03, 0.25 | |||
| ≥ vs. <90th percentile (Odds ratio, 95% CI) | 55/503 | 1.12 | 0.76, 1.64 | 54/485 | 1.00 | 0.70, 1.43 | 48/438 | 1.40 | 0.93, 2.09 |
| Presence of notching | |||||||||
| Unilateral (Odds ratio, 95% CI) | 133/420 | 1.10 | 0.85, 1.42 | 124/412 | 1.06 | 0.83, 1.35 | 117/368 | 1.23 | 0.94, 1.60 |
| Bilateral (Odds ratio, 95% CI) | 230/323 | 0.94 | 0.73, 1.21 | 128/408 | 0.91 | 0.69, 1.19 | 116/369 | 1.01 | 0.75, 1.36 |
a.
IQR for natural log-scaled values
b.
Models adjusted for maternal age, pre-pregnancy BMI, infant sex, parity, marital status, payment for prenatal care, maternal smoking, maternal race, maternal education
BMI, body mass index; CI, confidence interval; LUR, land use regression; NOx, nitrogen oxides; S/D, systolic/diastolic.