Skip to main content
. Author manuscript; available in PMC: 2019 Apr 25.
Published in final edited form as: Sci Transl Med. 2018 Apr 25;10(438):eaal1803. doi: 10.1126/scitranslmed.aal1803

Fig. 1. Chemical inactivation of BPL kills Mtb and prevents growth in macrophages.

Fig. 1

: (A) Impact of Bio-AMS on viability of Mtb in standard liquid culture. The dashed line indicates the limit of detection. (B) Impact of Bio-AMS on growth of Mtb with different carbon sources. Relative growth was calculated by dividing OD580 of the culture with Bio-AMS by the OD580 of the culture without Bio-AMS. (C) Impact of BioAMS on intracellular Mtb. Mouse bone marrow derived macrophages were infected and Bio-AMS or DMSO were added 24 h post infection. Data are representative of two independent experiments and averages 3 ± SEM (** P<0.01, Student’s t-test)