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. Author manuscript; available in PMC: 2019 Nov 29.
Published in final edited form as: Inflamm Bowel Dis. 2018 Nov 29;24(12):2565–2578. doi: 10.1093/ibd/izy242

TABLE 6:

IPA Analysis: Top Enriched Upstream Regulators

Upstream Regulator P of Overlap Activation
Z
Predicted
Activation State
Lipopolysaccharide 1.73 × 10−76 11.80 Activation
TNF 4.03 × 10−69 10.53 Activation
TGFB1 1.36 × 10−49 4.61 Activation
IL1B 5.68 × 10−46 10.31 Activation
IL13 7.74 × 10−46 2.32 Activation
IL4 1.26 × 10−44 3.11 Activation
IFNG 7.27 × 10−44 8.76 Activation
IL6 1.61 × 10−43 7.36 Activation
STAT3 2.15 × 10−42 6.41 Activation
Dexamethasone 4.44 × 10−42 –3.18 Inhibition