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. Author manuscript; available in PMC: 2018 Oct 17.
Published in final edited form as: Molecules. 2018 Sep 13;23(9):E2338. doi: 10.3390/molecules23092338

Figure 4.

Figure 4.

Kaempferol treatment for 12 weeks decreased hepatic glucose production from pyruvate and reduced PC activity without altering protein expressions of PC, PEPCK, or G6Pase in STZ-induced diabetic mice. PTT (a) was performed as described in the Method section, and the area under the curve (AUC) of PTT (b) was calculated. (c, g) PEPCK, (d, g) PC, and (e, g) G6Pase protein levels in the livers were measured by Western blot normalized to total protein contents in whole cell lysates. (f) PC activity was measured as described in the Method section. Data are shown as Mean ± SEM (n=8–9). *, P<0.05 vs. non-diabetic mice; # vs. STZ-induced diabetic mice. Control: nondiabetic mice; STZ: STZ-induced diabetic mice: STZ+Kaemp: STZ-induced diabetic mice treated with kaempferol (50mg/kg BW).