Skip to main content
. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: Hum Brain Mapp. 2018 Jul 27;39(12):4831–4843. doi: 10.1002/hbm.24326

Table II. MLR and CLR seed-to-ROI rsFC significantly associated with 6MWT distance (n=119).

Seed ROI
BnS #, orig #, label		 ROI centroid MNI coordinates (mm) Mean ± SD [95% CI] rsFC (Fisher z) 6MWT association T pFDR puncorrected
MLR 12, Bn12, right superior frontal gyrus medial area 9 6, 38, 35 0.09 ± 0.12 [0.07, 0.11] 3.96 0.0162 0.0002
MLR 253, S106, right paravermal cerebellum 7, −67, −21 0.21 ± 0.15 [0.18, 0.23] 3.57 0.0162 0.0004
CLR 67, Bn67, left paracentral lobule area 4 (M1F) −4, −23, 61 0.06 ± 0.13 [0.03, 0.08] −3.46 0.0486 0.0006

6MWT-rsFC association testing was non-parametric, two-sided, adjusted for age, sex, height and body mass index, and false-discovery rate (FDR) corrected for 81 ROI comparisons with a significance threshold of pFDR<0.05. MLR, midbrain locomotor region; CLR, cerebellar locomotor region; ROI, region of interest; rsFC, resting state functional connectivity; 6MWT, 6-minute walk test; Bn, Brainnetome Atlas; S, Shen Atlas; MNI, Montreal Neurological Institute space; CI, confidence interval; M1F, primary motor cortex foot area.