Table 2.
Baseline characteristics among participants with extended follow-up in the Trials of Hypertension Prevention by categories of % weight change during the intervention period.
| % Weight Change | P for Trend | ||||
|---|---|---|---|---|---|
| Lost > 5% | Lost 0-<= 5% | Gained 0-<5% | Gained 5%+ | ||
| MEN | |||||
| N | 372 | 788 | 1050 | 329 | |
| Change in weight during trial (lbs) | −20.4 | −4.4 | 4.6 | 16.9 | - |
| Baseline weight (lbs) | 213.9 | 212.0 | 214.4 | 216.7 | 0.042 |
| Active weight loss intervention (%) | 64.5 | 43.5 | 27.7 | 33.7 | <0.0001 |
| Active Na reduction intervention (%) | 31.4 | 34.5 | 36.5 | 39.8 | 0.014 |
| TOHP II (%) | 53.5 | 56.4 | 61.0 | 79.0 | <0.0001 |
| Age (yrs) | 43.4 | 43.8 | 43.1 | 41.6 | <0.0001 |
| Black (%) | 7.5 | 9.6 | 12.3 | 14.3 | 0.0007 |
| College (%) | 68.8 | 64.6 | 67.3 | 66.3 | 0.91 |
| Current smoker (%) | 8.6 | 9.1 | 9.7 | 9.7 | 0.50 |
| Past smoker (%) | 40.0 | 42.6 | 38.1 | 41.6 | 0.57 |
| Alcohol (% drinker) | 44.4 | 47.1 | 48.5 | 41.0 | 0.76 |
| Alcohol (drinks/wk among drinkers) | 6.7 | 7.4 | 7.2 | 7.2 | 0.61 |
| Exercise (% ≥once/wk) | 72.4 | 69.0 | 70.5 | 76.2 | 0.26 |
| SBP (mmHg) | 126.3 | 126.1 | 126.2 | 126.0 | 0.63 |
| DBP (mmHg) | 84.9 | 85.2 | 85.3 | 85.3 | 0.021 |
| Sodium (mmol/24hr) | 169.8 | 172.6 | 175.9 | 186.1 | 0.0002 |
| Potassium (mmol/24hr) | 70.1 | 67.3 | 65.5 | 67.1 | 0.006 |
| WOMEN | |||||
| N | 184 | 313 | 517 | 275 | |
| Change in weight during trial (lbs) | −18.0 | −4.0 | 3.8 | 16.2 | - |
| Baseline weight (lbs) | 180.1 | 181.7 | 179.4 | 179.5 | 0.44 |
| Active weight loss intervention (%) | 50.0 | 40.6 | 32.7 | 40.4 | 0.011 |
| Active Na reduction intervention (%) | 32.6 | 37.4 | 34.6 | 41.4 | 0.13 |
| TOHP II (%) | 58.7 | 63.6 | 56.9 | 74.9 | 0.007 |
| Age (yrs) | 44.2 | 44.7 | 43.9 | 43.3 | 0.028 |
| Black (%) | 22.3 | 31.0 | 33.1 | 32.0 | 0.033 |
| College (%) | 45.1 | 48.2 | 44.1 | 44.0 | 0.47 |
| Current smoker (%) | 11.4 | 13.1 | 10.2 | 10.9 | 0.50 |
| Past smoker (%) | 28.3 | 25.9 | 25.2 | 27.6 | 0.88 |
| Alcohol (% drinker) | 26.6 | 24.3 | 23.0 | 22.2 | 0.25 |
| Alcohol (drinks/wk among drinkers) | 5.1 | 5.3 | 5.2 | 5.4 | 0.72 |
| Exercise (% ≥once/wk) | 62.8 | 55.8 | 56.3 | 58.4 | 0.50 |
| SBP (mmHg) | 126.7 | 127.2 | 127.4 | 126.8 | 0.84 |
| DBP (mmHg) | 85.0 | 84.9 | 85.1 | 85.3 | 0.097 |
| Sodium (mmol/24hr) | 130.5 | 128.9 | 138.0 | 143.4 | <0.0001 |
| Potassium (mmol/24hr) | 53.7 | 50.0 | 49.4 | 51.7 | 0.25 |
Data represent means or percentages. SBP indicates systolic blood pressure; DBP, diastolic blood pressure; Na, sodium.