Table 1.

Patient demographics and ECG parameters based on category of left ventricular ejection fraction (LVEF) in the Cedars-Sinai Health System validation population. All ECG parameters differed significantly between subjects with LVEF ≤35% and those with LVEF >35%.

	Cedars-Sinai Validation Population† (n=9742)
	LVEF ≤35% (n=875)	LVEF >35% (n=8799)	p-value
Demographics
Male	648 (74%)	4554 (52%)	<0.001
Age	68.0 ± 16.1	68.7 ± 17.3	0.23
Conventional abnormal electrocardiographic findings
Left bundle branch block (LBBB)	101 (12%)	266 (3%)	<0.001
Atrial fibrillation / flutter	128 (15%)	864 (9%)	<0.001
Ventricular paced rhythm	186 (21%)	437 (5%)	<0.001
≥1 Conventional ECG abnormality	388 (44%)	1508 (17%)	<0.001
	Cedars-Sinai Validation Population without conventional abnormal ECG findings† (n=7601)
	LVEF ≤35% (n=461)	LVEF >35% (n=7140)	p-value
Demographics
Male	336 (73%)	3660 (51%)	<0.001
Age	63.8 ± 16.3	66.3 ± 17.4	0.003
Expanded panel of electrocardiographic variables in subset without conventional ECG abnormalities
Heart rate >85bpm	215 (47%)	2193 (31%)	<0.001
QRS >110ms	170 (37%)	1017 (14%)	<0.001
Prolonged QTc‡ ≥460ms men and ≥470ms women	311 (67%)	1981 (28%)	<0.001
QRS-T angle >90o‡	259 (56%)	1300 (18%)	<0.001
Delayed QRS transition‡	303 (66%)	2149 (30%)	<0.001
Delayed intrinsicoid deflection‡	156 (34%)	412 (5.8%)	<0.001
Left ventricular hypertrophy	68 (15%)	459 (6.4%)	<0.001
PR >200ms‡	89 (19%)	834 (12%)	<0.001
P-wave >110ms‡	126 (27%)	1303 (18%)	<0.001

Data are presented as n (%) or mean ±SD.

^†Validation population: n=9742 inpatients and outpatients from the Cedars-Sinai hospital system with LVEF assessed by echocardiogram from Jan. 1 – Dec. 31, 2015 and ECG available within 14 days of the echocardiogram. Conventional ECG abnormalities evaluated in n=9674 patients without acute MI; Expanded panel of ECG abnormalities evaluated in n=7601 patients without conventional abnormalities (ECGs in sinus rhythm and without LBBB).