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. Author manuscript; available in PMC: 2019 Feb 28.
Published in final edited form as: FEBS J. 2018 Nov 23;286(1):169–183. doi: 10.1111/febs.14695

Figure 2. Comparison of VIM Active Sites.

Figure 2.

A. Active site of VIM-1, showing positions of His224 and Ser228 and location of Cys221-bound water Wat3. Hydrogen bonding interactions are shown as dashed lines. B. Active site superpositions of VIM-2 (pdb 4BZ3, blue) and VIM-4 (pdb 2WHG, red) showing variations at positions 224 and 228.