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A. Interactions made by hydrolysed meropenem with VIM-1 active site. Hydrogen bonds are shown as dashed lines. B. Map of VIM-1 interactions with hydrolysed meropenem. Zinc ions are rendered in green; water molecules in cyan; other atom colours as standard. C. Structure of intact and hydrolysed meropenem in Δ2 (B) and Δ1 (C) pyrroline forms.
