Table 2.
Sample Characteristics and Baseline Primary Outcome Measures by NMR Group
| Characteristic | NMR Group, Mean (SD)a | |
|---|---|---|
| Slow (n = 41) | Fast (n = 59) | |
| Age, y | 42.90 (12.39) | 43.10 (12.04) |
| Sex, No. (%)b | ||
| Men | 34 (82.9) | 39 (66.1) |
| Women | 7 (17.1) | 20 (33.9) |
| BMIb | 28.47 (6.50) | 26.33 (5.26) |
| Race, No. (%)c | ||
| White | 21 (51.2) | 53 (89.8) |
| Black/African American | 13 (31.7) | 5 (8.5) |
| Other | 7 (17.1) | 1 (1.7) |
| Ethnicity, No. (%) | ||
| Non-Hispanic | 37 (94.9) | 58 (98.3) |
| Hispanic/Latino | 2 (5.1) | 1 (1.7) |
| Cigarettes per day, No. | 17.24 (6.98) | 17.36 (4.72) |
| Years smoking | 26.27 (12.47) | 26.20 (11.97) |
| Nicotine dependence, FTND score | 5.59 (1.75) | 5.41 (1.83) |
| NMRc | 0.19 (0.06) | 0.57 (0.17) |
| Baseline outcome measures | ||
| Cigarettes per day, No. | 14.11 (5.32) | 15.69 (6.07) |
| Total puff volume, mL | 761.03 (255.00) | 767.73 (298.08) |
| TNE, nmoL/mg creatinined | 56.26 (8.76) | 75.19 (12.06) |
| NNAL, pg/mg creatinined | 217.02 (2.34) | 343.78 (12.06) |
| Onset CO level, ppm | 19.16 (9.72) | 20.65 (8.21) |
| CO boost, ppm | 4.03 (2.17) | 4.32 (2.49) |
Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); CO, carbon monoxide; FTND, Fagerström Test for Nicotine Dependence; NMR, nicotinemetabolite ratio; NNAL, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol; TNE, total nicotine equivalents.
a
Data are presented as arithmetic mean (SD) for all continuous measures except NNAL and TNE, which are presented as geometric mean (SD); data are presented as number (valid percentage) for categorical measures.
b
Significant at the P < .10 level.
c
Significant at the P < .001 level.
d
Significant at the P < .05 level.