Skip to main content
. Author manuscript; available in PMC: 2009 Feb 3.
Published in final edited form as: Protein Expr Purif. 2007 Oct 24;57(2):206–216. doi: 10.1016/j.pep.2007.10.013

Fig. 1.

Fig. 1

Schematic representation of the hCD81 protein produced in this study. The mutated palmitoylation sites (Cys to Ala) are highlighted as white circles in the sequence. The His6 tag is indicated as a rectangle in the carboxy-terminal tail. The two extracellular loops are marked as EC1 and EC2. EC2 contains the conserved Cys-Cys-Gly (CCG) motif associated with the tetraspanin family. The published crystal structure of soluble EC2 indicates the importance of this motif in forming the disulfide bridges represented in the figure. The membrane is represented in grey.