Scheme 20.
Summary of Zhu’s approach to the diversity-oriented synthesis of polyheterocycles and pyrrolopyridines. Reagents and conditions: (1) MeOH, rt, [R1 = Bn, R2 = CO2Et, R3 = C6H13, R4 = Bn, 92%]; (2) MeOH, TFA, −78 °C, [R1 = Bn, R2 = CO2Et, R3 = C6H13, R4 = Bn, 85%].