(a) LUCA-15/RBM5 is capable of inducing cell cycle arrest in G1-M and apoptosis.
DNA content from CEM-C7/pcDNA3 and CEM-C7/pcDNA3-RBM5 was quantified by propidium iodide staining of fixed cells.
(b) LUCA -15Δ6 overexpression results in an increase in cells in S and G2/M phases and a concomitant decrease in G1 cells, producing an increase in proliferation rate.