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. Author manuscript; available in PMC: 2010 Aug 10.
Published in final edited form as: Blood. 2010 Mar 22;115(23):4878–4885. doi: 10.1182/blood-2009-11-256610

Table 1. Protein S variants generated by site directed mutagenesis.

GLA1 D38N/V46G/K97Q
GLA2/Face2 L21T/N23S/K24Y/R28F/D34S/Y41W/L45T
TSR1 R49Q/R60Q/D68N/R70Q/D78N
EGF1 single
residue variants
K94A, D95A, K97A, S99A, T101A, T103A, K105A, P106A, W108A,
Q109A, E111A, K112A
EGF2 single
residue variants
D135A, N136A, T137A, Y141A, H142A, S144A, K146A, S153A,
N154A, K155A, K156A, D157A