Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Mechanisms of anti-idiotypic antibodies on effector cells. Mediator release of effector cells (E) is triggered by cross-linkage of 2 receptor-bound IgE either via (A) recognition of the antigen or (B) the anti-id. (C) Effector cell inhibition is achieved by binding of the anti-id to its specific idiotype within a polyclonal response. (D) Cross-linkage of FcεRI and the inhibitory FcγRIIb receptor via an anti-idiotypic IgG antibody also inhibits degranulation.
