Table 3.

Reclassification of population of 100,00 women 35-79 years eligible for screening and in whom breast cancer could be detectable, under age-based or personalised screening strategies. Eligibility based on age 47 or polygenic risk equivalent to 10-year absolute risk for age 47 (2.5 percent 10-year absolute risk); England 2002-2006

Personalised screening	Age-based screening
Polygenic risk threshold	< 47 years	≥ 47 years	Total
Population
< 2.5%	30,276	19,926	50,202
≥ 2.5%	4,429	45,368	49,798
Total	34,705	65,295	100,000
Cases
< 2.5%	26	38	64
≥ 2.5%	9	162	172
Total	35	200	236