Table 1. Cys-loop aromatic box residuesa.
Receptor | Loop A | Loop B | Loop C | Loop D | |
---|---|---|---|---|---|
nAChR | Y93 | W149 | Y190 | Y198 | W55 |
5-HT3 | E129b | W183 | F226 | Y234 | W90 |
MOD-1 | C120 | Y180 | Y221 | W226 | F83 |
GABAC | F138 | Y198 | Y241 | Y247 | Y102 |
GABAA | Y97 | Y157 | F200 | Y205 | F65 |
Residues previously identified as contributing to cation-π bonds are typed in bold.