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. Author manuscript; available in PMC: 2009 Mar 2.
Published in final edited form as: J Neurosci. 2007 Jan 24;27(4):886–892. doi: 10.1523/JNEUROSCI.4791-06.2007

Table 3. Functional characterization of β297 mutant GABAA receptors.

Mutant LogEC50 ± SEM EC50 (μm) EC50mut/EC50phe n H n
α 1 β 2 −5.457 ± 0.04 3.5 1.2 4
α 1 β 2 97-Phe −6.190 ± 0.16a 0.6 1 1.4 4
α 1 β 2 97-4-F-Phe −4.706 ± 0.07a 20 33 1.2 5
α 1 β 2 97-3,5-F2-Phe −3.372 ± 0.05a 420 700 1.1 4
α 1 β 2 97-3,4,5-F3-Phe −2.002 ± 0.04a 9900 16,500 1.9 5
a

Denotes logEC50 values statistically significantly different from wild type by one-way ANOVA; p < 0.01.