Figure 1.

(A) Ischemia scan series and (B) post-reperfusion scan series, with regions of interest (ROIs) superimposed on the apparent diffusion coefficient (ADC) maps (images Aiv and Biv); (ii) ${\mathrm{T}}_2^{\ast }$ oxygen challenge (OC) percentage signal change map, (iii) thresholded ${\mathrm{T}}_2^{\ast }$ OC map, (v) cerebral blood flow (CBF) map (mL per 100 g per minute), and (vi) DWI/PWI overlay (mismatch tissue shown in red). ROIs were defined as follows: green ROI—the penumbra was defined by applying a threshold to display the greatest ${\mathrm{T}}_2^{\ast }$ percentage signal change excluding veins and ventricles (iii). Red ROI—ischemic core within the caudate nucleus, derived from the ADC lesion (i). Sky blue ROI—the contralateral cortex, equivalent to OC-defined penumbra. Cerise ROI—the contralateral caudate nucleus, equivalent to the ADC-derived lesion. Dark blue ROI— DWI/PWI mismatch (vi) derived from the thresholded ADC (i) and CBF maps (v).