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. Author manuscript; available in PMC: 2012 Aug 1.
Published in final edited form as: Cancer Prev Res (Phila). 2011 Nov 14;5(2):164–178. doi: 10.1158/1940-6207.CAPR-11-0391

Figure 3.

Figure 3

Possible sites of action of aspirin in the prevention of colorectal cancer. COX-dependent and independent targets of aspirin are likely to be present in both epithelial and stromal cell compartments in colorectal adenomas and cancers. ATLs, aspirin-triggered lipoxins; COX, cyclooxygenase; PGE2, prostaglandin E2; S-1P, sphingosine-1-phosphate.