Table 3.
Summary of approved preventative schedules for helminthic diseases (adapted from http://whqlibdoc.who.int/publications/2006/9241547103_eng.pdf) a
| Disease | Treatment |
|---|---|
| LF | Treat entire population at risk with ALB + DEC or ALB + IVN |
| LF + Onchocerciasis | Treat entire population at risk with ALB + IVN |
| LF + Schistosomiasis | Round 1: Treat entire population at risk with ALB + DEC or ALB + IVN Round 2 (at least one week after round 1): Treat school-age children and adults at risk with PZQ |
| LF + STH | Round 1: Treat entire population at risk with ALB + DEC or ALB + IVN Round 2 (after 6 months): If STH prevalence ≥ 50%, treat school-age children with ALB or MEB |
| LF + Onchocerciasis + Schistosomiasis | Round 1: Treat entire population at risk with ALB + IVN Round 2 (at least one week after round 1): Treat school-age children and adults at risk with PZQ |
| LF + Onchocerciasis + STH | Round 1: Treat entire population at risk with ALB + IVN Round 2 (after 6 months): If STH prevalence ≥ 50%, treat school-age children with ALB or MEB |
| Onchocerciasis | Treat entire population at risk in meso- & hyper-endemic communities with IVN |
| Onchocerciasis + Schistosomiasis | Round 1: Treat entire population at risk in meso- & hyper-endemic communities with IVN Round 2 (at least one week after round 1): Treat school-age children and adults at risk with PZQ |
| Onchocerciasis + STH | Round 1: ALB (treat school-age children) and IVN (treat entire population at risk in meso- & hyper-endemic communities) Round 2 (after 6 months): If STH prevalence ≥ 50%, treat school-age children with ALB or MEB |
| Schistosomiasis | Treat school-age children and adults at risk with PZQ |
| Schistosomiasis + STH | Round 1: ALB or MEB (treat school-age children) and PZQ (treat school-age children and adults considered at risk) Round 2 (after 6 months): If STH prevalence ≥ 50%, treat school-age children with ALB or MEB |
| STH | Round 1: Treat school-age children with ALB or MEB Round 2 (after 6 months): If STH prevalence ≥ 50%, treat school-age children with ALB or MEB |
a
Note: ALB = albendazole, DEC = diethylcarbamazine, IVN = ivermectin, MEB = mebendazole, PZQ = praziquantel; LF, lymphatic filariasis; STH, soil-transmitted helminths