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. Author manuscript; available in PMC: 2009 May 22.
Published in final edited form as: Biol Psychiatry. 2008 May 7;64(5):438–442. doi: 10.1016/j.biopsych.2008.03.028

Table 2.

Association Between Single SNP and Disease Status in Phase I, Combined Phase I and Phase II, and Familial Cases Using HRR Analysis

Bipolar Spectrum Disorder
 Psychotic Disorder
Phase I
(62 Families)		 Phase I + II
(154 Families)		 Familial Casesa
(99 Families)		 Phase I
(57 Families)		 Phase I + II
(144 Families)		 Familial Casesa
(102 Families)
DAOA
     rs3916966 .696 .966 .906 .843 .839 .616
     rs2391191 .889 .913 .735 .87 .891 .349
     rs2153674 .072 .353 .095 .066 .700 .233
     rs701567 .670 .593 .407 .278 .133 .031
     rs778326 .025 .111 .024 .010 .186 .018
     rs954580 .040 .107 .052 .049 .565 .252
COMT
     rs4680 .085 .046 .020 .340 .072 .149
     rs165599 .003 .829 .035 .015 .396 .103

COMT, catechol-O-methyl transferase; DAOA, d-amino acid oxidase activator; HRR, haplotype relative risk; SNP, single nucleoide polymorphism.

a

Familial cases include only families that contain at least two affected individuals.