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. Author manuscript; available in PMC: 2012 May 16.
Published in final edited form as: Hum Brain Mapp. 2010 Feb 16;31(12):1886–1899. doi: 10.1002/hbm.20979

Figure 4.

Figure 4

Activity involved in action-selection versus specified trials corrected for multiple comparisons (FDR < 0.05). (A) Increased activity for action-selection in wide bilateral network. including: dorsal and ventro -lateral prefrontal cortex, middle and inferior frontal gyrus, SMA and premotor cortex, inferior parietal cortex, right supramarginal gyrus, fusiform gyrus, and cerebellum. (B) In the patient group action-selection activity was modulated by UPDRS in left lateral prefrontal cortex, bilateral inferior premotor cortex and left insula when “on” (Masked by Action-selection vs. Specified contrast at FDR P < 0.05). Plots of peak activity across UPDRS scores show how BOLD response declines with more severe disease, age-matched control subjects are also presented (gray lines) to show normal range.