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. 1975 Nov 15;4(5993):381–383. doi: 10.1136/bmj.4.5993.381

H-rosette formation in T-cell-proliferative diseases.

P J Sheldon, E J Holborow
PMCID: PMC1675253  PMID: 127645

Abstract

In health up to 6% of human lymphocytes will form rosettes with homologous group O rhesus-negative erythrocytes (H rosettes). Increased numbers of H rosettes were found in T-cell-proliferative diseases-- namely, infectious mononucleosis, Sézary's syndrome, and T-cell leukaemia. H-rosette formation is thus a marker for a subpopulation of T lymphocytes, and this easily performed test of T-cell activation may have clinical value in characterising changes in blood lymphocyte populations in disease.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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