Abstract
Two intranasal biopsies of human olfactory mucosa were studied with the electron microscope, after confirming with the light microscope that they were in fact from the olfactory region. It was noted that the end of the dendrite of the human olfactory cell is flat or dome-shaped, and is not a bulb-like projection (olfactory vesicle). Moreover, the cilia are in the long axis of the olfactory cell, perpendicular to the epithelial surface, and do not lie parallel to it as described in some species. The supporting cells had multiple long microvilli, and definite points of contact with the olfactory cells; they appeared to spread their secretion over the microvilli in a novel manner, producing a layer of regularly spaced, spike-like granules.
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- Arstila A., Wersäll J. The ultrastructure of the olfactory epithelium of the guinea pig. Acta Otolaryngol. 1967 Sep;64(3):187–204. doi: 10.3109/00016486709139106. [DOI] [PubMed] [Google Scholar]
- DE LORENZO A. J. Electron microscopy of the olfactory and gustatory pathways. Ann Otol Rhinol Laryngol. 1960 Jun;69:410–420. doi: 10.1177/000348946006900210. [DOI] [PubMed] [Google Scholar]
- Jourdan F. Ultrastructure de l'épithélium olfactif du rat: polymorphisme des récepteurs. C R Acad Sci Hebd Seances Acad Sci D. 1975 Jan 27;280(4):443–446. [PubMed] [Google Scholar]
- LE GROS CLARK W. E. Observations on the structure and organization of olfactory receptors in the rabbit. Yale J Biol Med. 1956 Nov;29(2):83–95. [PMC free article] [PubMed] [Google Scholar]
- LUFT J. H. Improvements in epoxy resin embedding methods. J Biophys Biochem Cytol. 1961 Feb;9:409–414. doi: 10.1083/jcb.9.2.409. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Loo S. K. Fine structure of the olfactory epithelium in some primates. J Anat. 1977 Feb;123(Pt 1):135–145. [PMC free article] [PubMed] [Google Scholar]
- Moulton D. G., Beidler L. M. Structure and function in the peripheral olfactory system. Physiol Rev. 1967 Jan;47(1):1–52. doi: 10.1152/physrev.1967.47.1.1. [DOI] [PubMed] [Google Scholar]
- Okano M., Weber A. F., Frommes S. P. Electron microscopic studies on the distal border of the canine olfactory epithelium. J Ultrastruct Res. 1967 Mar;17(5):487–502. doi: 10.1016/s0022-5320(67)80137-0. [DOI] [PubMed] [Google Scholar]
- Peachey L. D. The sarcoplasmic reticulum and transverse tubules of the frog's sartorius. J Cell Biol. 1965 Jun;25(3 Suppl):209–231. doi: 10.1083/jcb.25.3.209. [DOI] [PubMed] [Google Scholar]
- REYNOLDS E. S. The use of lead citrate at high pH as an electron-opaque stain in electron microscopy. J Cell Biol. 1963 Apr;17:208–212. doi: 10.1083/jcb.17.1.208. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Willemot J. La muqueuse olfactive chez l'homme vivant. Etude histochimique. Acta Otolaryngol. 1971 Feb-Mar;71(2):197–205. [PubMed] [Google Scholar]