Abstract
OBJECTIVE: The authors examined the resectability, operative morbidity mortality, and survival of patients with pancreatic adenocarcinoma of the body and tail compared with lesions in the head. SUMMARY BACKGROUND DATA: Adenocarcinoma of the body and tail of the pancreas is characteristically thought of as a disease that presents late and rarely is operable or resectable. METHODS: In an 11-year period, 1981 patients were admitted and entered into a prospective database at Memorial Sloan-Kettering Cancer Center with a diagnosis of peripancreatic cancer, 1363 of whom had adenocarcinoma of the pancreas, 75% with lesions in the head and 25% with lesions in the body and tail. RESULTS: Of 271 patients resected, 237 (23%) had lesions in the head and 34 (10%) had body and tail lesions. Perioperative mortality was 4% for patients with pancreatic lesions in the head and 0% for patients with pancreatic lesions in the body and tail. Five-year actuarial survival for body and tail lesions was projected at 14% for 5 years. Actual survival was 19%, with three patients alive for more than 5 years. CONCLUSIONS: Adenocarcinoma of the body and tail of the pancreas, although less likely to be resectable at presentation than lesions in the pancreatic head, have similar postresection survival.
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- Dalton R. R., Sarr M. G., van Heerden J. A., Colby T. V. Carcinoma of the body and tail of the pancreas: is curative resection justified? Surgery. 1992 May;111(5):489–494. [PubMed] [Google Scholar]
- Geer R. J., Brennan M. F. Prognostic indicators for survival after resection of pancreatic adenocarcinoma. Am J Surg. 1993 Jan;165(1):68–73. doi: 10.1016/s0002-9610(05)80406-4. [DOI] [PubMed] [Google Scholar]
- Johnson C. D., Schwall G., Flechtenmacher J., Trede M. Resection for adenocarcinoma of the body and tail of the pancreas. Br J Surg. 1993 Sep;80(9):1177–1179. doi: 10.1002/bjs.1800800937. [DOI] [PubMed] [Google Scholar]
- Jordan G. L., Jr Pancreatic resection for pancreatic cancer. Surg Clin North Am. 1989 Jun;69(3):569–597. doi: 10.1016/s0039-6109(16)44836-x. [DOI] [PubMed] [Google Scholar]
- Nordback I. H., Hruban R. H., Boitnott J. K., Pitt H. A., Cameron J. L. Carcinoma of the body and tail of the pancreas. Am J Surg. 1992 Jul;164(1):26–31. doi: 10.1016/s0002-9610(05)80641-5. [DOI] [PubMed] [Google Scholar]
- Saltzman A., Horvitz A., Dyckman J. Survival for 25 years following partial pancreatectomy for carcinoma of the body of the pancreas. Mt Sinai J Med. 1987 Jun;54(5):427–428. [PubMed] [Google Scholar]