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. 2025 Nov 6;12(1):2580853. doi: 10.1080/20018525.2025.2580853

Correction

PMCID: PMC12599339  PMID: 41221155

Article title: Airway hyperresponsiveness to mannitol in relation to inspiratory and expiratory resistance in subjects with asthma, COPD, and healthy smokers

Authors: Abir Nasr, Georgia Papapostolou, Linnea Jarenbäck, Kerstin Romberg, Alf Tunsäter, Jaro Ankerst, Leif Bjermer and Ellen Tufvesson

Journal: European Clinical Respiratory Journal

Bibliometrics: Volume 12, Number 01, pages 1-12

DOI: https://doi.org/10.1080/20018525.2025.2546677

It has been noted by the authors that Tables 1 and 2 were not included in the originally published article. The correct Tables 1 and 2 are provided below, and the original article has been updated to include them.

Table 1.

Subject characteristics.

  Asthma Healthynever-smokers   COPD Healthy smoker    
 
n=239
n=15
p-valuee
n=25
n=14
p-valuef
p-valueg
Age, years 49(34–58) 47(34–66) 0.62 69(66–74) 60(58–67) 0.0043 <0.0001
Sex, females/males,n (%) 127/112
(53/47)
8/7(53/47) 0.98 20/5
(80/20)
8/6(57/43) 0.13 0.01
Height, m 1.73(1.67–1.80) 1.74(1.69–1.81) 0.86 1.65(1.61–1.72) 1.70(1.67–1.79) 0.021 0.0002
BMI, kg/m2 25 (23–28) 23 (22–25) 0.12 26 (24–29) 26(22–31) 0.57 0.18
FeNOa, ppb 19 (12-31) 20 (15-24) 0.86 13(9-18) 8 (6–12) 0.04 0.0027
Atopyb, n (%) 148 (62) n.d. n.a. 1 (4) 0 >0.99 <0.0001
Eosinophilc 0.2 (0.10–0.3) 0.1(0.1-0.15) 0.019 0.2 (0.2–0.4) 0.1(0.1–0.2) 0.0088 0.24
Non-smoker/ex-smokerd/smoker, n 157/8/74 15/0/0 0.021 1/17/7 0/2/12 0.001 <0.001
Packyears 0(0–1) n. a. n.a 26(13–39) 38(30–48) 0.061 <0.0001

Data is presented as median (IQR) if not otherwise stated.

aFeNO was missing in 10 subjects (5 asthma, 1 healthy never-smoker, 3 COPD and 1 healthy smoker).bOne missing phadiatop test (atopy) in COPD.cEosinophil test was not performed in 8 subjects (1 asthma and 7 healthy never-smokers).dEx-smokers were defined as former smokers with ≥ 5 pack-years of smoking history.

eComparison between asthma and healthy never-smokers.fComparison between COPD and healthy smokers. gComparison between asthma and COPD.

n. a.=non-applicable, BMI=body mass index, FeNO=fractional exhaled NO.

Table 2.

Correlations between the relative change in % from baseline to last dose in FEV1 (=Δ%FEV1) and in respiratory oscillometry indices (Δ%R5, Δ%R19 and Δ%X5) among subjects with negative and positive mannitol test.

    Δ%R5insp Δ%R5exp Δ%R19insp Δ%R19exp Δ%X5insp Δ%X5exp
Asthma              
Neg. mannitol test r 0.049 0.12 0.031 0.020 0.019 0.11
  p 0.54 0.13 0.70 0.80 0.82 0.18
Pos. mannitol test r 0.013 -0.016 0.10 -0.044 -0.12 -0.044
  p 0.91 0.89 0.35 0.69 0.28 0.69
COPD              
Neg. mannitol test r 0.35 0.23 0.22 -0.28 0.67 0.27
  p 0.27 0.47 0.50 0.38 0.02 0.39
Pos. mannitol test r 0.028 0.46 0.17 0.24 0.38 0.44
  p 0.93 0.11 0.57 0.42 0.19 0.13
Healthy Smokers              
Neg. mannitol test r 0.57 0.11 -0.14 -0.25 0.32 -0.50
  p 0.20 0.84 0.78 0.59 0.50 0.27
Pos. mannitol test r -0.36 -0.82 -0.75 -0.82 -0.64 -0.32
  p 0.44 0.034 0.066 0.034 0.14 0.50

r=Spearman´s rank correlation coefficient.

This correction does not affect the description, interpretation, or conclusions of the article.


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