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. 1987 Apr;71:69–75. doi: 10.1289/ehp.877169

Advantages of using aquatic animals for biomedical research on reproductive toxicology.

N K Mottet, M L Landolt
PMCID: PMC1474364  PMID: 3297666

Abstract

Major advantages of the use of aquatic animals, such as trout, English sole, or sea urchins, for studying the mechanisms of reproductive toxicology are discussed. The remarkable synchrony of differentiation of gametes in large quantities for detailed morphologic and biochemical measurements enables research not readily done on mammalian nonseasonal breeders. Structural differences such as the absence of a fibrous sheath in the more simple structure of fish and sea urchin sperm flagella facilitates comparative study of the mechanism of action of microtubules in flagella movement and the coupling of mitochondrial energy production to microtubules movement.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Billard R., Reinaud P., Le Brenn P. Effects of changes of photoperiod on gametogenesis in the rainbow trout (Salmo gairdneri). Reprod Nutr Dev. 1981;21(6A):1009–1014. doi: 10.1051/rnd:19810713. [DOI] [PubMed] [Google Scholar]
  2. CLERMONT Y. Quantitative analysis of spermatogenesis of the rat: a revised model for the renewal of spermatogonia. Am J Anat. 1962 Sep;111:111–129. doi: 10.1002/aja.1001110202. [DOI] [PubMed] [Google Scholar]
  3. Christen R., Schackmann R. W., Shapiro B. M. Metabolism of sea urchin sperm. Interrelationships between intracellular pH, ATPase activity, and mitochondrial respiration. J Biol Chem. 1983 May 10;258(9):5392–5399. [PubMed] [Google Scholar]
  4. Crim L. W., Evans D. M. Influence of testosterone and/or luteinizing hormone releasing hormone analogue on precocious sexual development in the juvenile rainbow trout. Biol Reprod. 1983 Aug;29(1):137–142. doi: 10.1095/biolreprod29.1.137. [DOI] [PubMed] [Google Scholar]
  5. Dentler W. L., Rosenbaum J. L. Flagellar elongation and shortening in Chlamydomonas. III. structures attached to the tips of flagellar microtubules and their relationship to the directionality of flagellar microtubule assembly. J Cell Biol. 1977 Sep;74(3):747–759. doi: 10.1083/jcb.74.3.747. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Drance M. G., Hollenberg M. J., Smith M., Wylie V. Histological changes in trout testis produced by injections of salmon pituitary gonadotropin. Can J Zool. 1976 Aug;54(8):1285–1293. doi: 10.1139/z76-146. [DOI] [PubMed] [Google Scholar]
  7. Evenson D. P., Darzynkiewicz Z., Melamed M. R. Relation of mammalian sperm chromatin heterogeneity to fertility. Science. 1980 Dec 5;210(4474):1131–1133. doi: 10.1126/science.7444440. [DOI] [PubMed] [Google Scholar]
  8. Evenson D. P., Melamed M. R. Rapid analysis of normal and abnormal cell types in human semen and testis biopsies by flow cytometry. J Histochem Cytochem. 1983 Jan;31(1A):248–253. [PubMed] [Google Scholar]
  9. Funk J. D., Donaldson E. M. Induction of precocious sexual maturity in male pink salmon (Oncorhynchus gorbuscha). Can J Zool. 1972 Nov;50(11):1413–1419. doi: 10.1139/z72-190. [DOI] [PubMed] [Google Scholar]
  10. Hacker U., Schumann J., Göhde W. Effects of acute gamma-irradiation on spermatogenesis as revealed by flow cytometry. Acta Radiol Oncol. 1980;19(5):361–368. doi: 10.3109/02841868009131321. [DOI] [PubMed] [Google Scholar]
  11. Huckins C. The morphology and kinetics of spermatogonial degeneration in normal adult rats: an analysis using a simplified classification of the germinal epithelium. Anat Rec. 1978 Apr;190(4):905–926. doi: 10.1002/ar.1091900410. [DOI] [PubMed] [Google Scholar]
  12. McIntyre J. D. Toxicity of methyl mercury for steelhead trout sperm. Bull Environ Contam Toxicol. 1973 Feb;9(2):98–99. doi: 10.1007/BF01684762. [DOI] [PubMed] [Google Scholar]
  13. Mohamed M. K., Lee W. I., Mottet N. K., Burbacher T. M. Laser light-scattering study of the toxic effects of methylmercury on sperm motility. J Androl. 1986 Jan-Feb;7(1):11–15. doi: 10.1002/j.1939-4640.1986.tb00858.x. [DOI] [PubMed] [Google Scholar]
  14. Morisawa M., Mori H. Heavy metals and spermatozoan motility. II. Turbidity changes induced by divalent cations and adenosinetriphosphate in sea urchin sperm flagella. Exp Cell Res. 1974 Jan;83(1):87–94. doi: 10.1016/0014-4827(74)90691-0. [DOI] [PubMed] [Google Scholar]
  15. Ogawa K., Negishi S., Obika M. Dynein 1 from rainbow trout spermatozoa: immunological similarity between trout and sea urchin dynein 1. Arch Biochem Biophys. 1980 Aug;203(1):196–203. doi: 10.1016/0003-9861(80)90169-1. [DOI] [PubMed] [Google Scholar]
  16. Popescu H. I. Poisoning with alkylmercury compounds. Br Med J. 1978 May 20;1(6123):1347–1347. doi: 10.1136/bmj.1.6123.1347-a. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Roosen-Runge E. C. Germinal-cell loss in normal metazoan spermatogenesis. J Reprod Fertil. 1973 Nov;35(2):339–348. doi: 10.1530/jrf.0.0350339. [DOI] [PubMed] [Google Scholar]
  18. Roth L. E., Shigenaka Y. Microtubules in the heliozoan axopodium. II. Rapid degradation by cupric and nickelous ions. J Ultrastruct Res. 1970 May;31(3):356–374. doi: 10.1016/s0022-5320(70)90138-3. [DOI] [PubMed] [Google Scholar]
  19. Salmon E. D., Segall R. R. Calcium-labile mitotic spindles isolated from sea urchin eggs (Lytechinus variegatus). J Cell Biol. 1980 Aug;86(2):355–365. doi: 10.1083/jcb.86.2.355. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Shapiro B. M., Schackmann R. W., Gabel C. A. Molecular approaches to the study of fertilization. Annu Rev Biochem. 1981;50:815–843. doi: 10.1146/annurev.bi.50.070181.004123. [DOI] [PubMed] [Google Scholar]
  21. Vogel D. G., Margolis R. L., Mottet N. K. The effects of methyl mercury binding to microtubules. Toxicol Appl Pharmacol. 1985 Sep 30;80(3):473–486. doi: 10.1016/0041-008x(85)90392-8. [DOI] [PubMed] [Google Scholar]
  22. van den Hurk R., Peute J., Vermeij J. A. Morphological and enzyme cytochemical aspects of the testis and vas deferens of the rainbow trout, Salmo gairdneri. Cell Tissue Res. 1978 Jan 17;186(2):309–325. doi: 10.1007/BF00225540. [DOI] [PubMed] [Google Scholar]

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