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In the article above, the following correction should be made to Question 1, Answer D: Mixed cryoglobulinemia describes both type II and type III cryoglobulinemia. Both types II and III are comprised of rheumatoid factors, which are antibodies that bind to the Fc fragment of IgG. In type II cryoglobulinemia, cryoglobulins consist of monoclonal IgM and polyclonal IgG, while in type III cryoglobulinemia, cryoglobulins are composed of polyclonal IgM and IgG.