Corrigendum to Knockdown of ubiquitin-specific protease 53 enhances the radiosensitivity of human cervical squamous cell carcinoma by regulating DNA damage-binding protein 2. Technology in Cancer Research and Treatment 19(1): 1–7. DOI: 10.1177/1533033820929792
On P. 3 in Results section, paragraph 2 should be read as follows:
After a period of regular radiotherapy and chemotherapy, the curative effect (SD, PR, CR) is evaluated by the clinician based on the test results and clinical symptoms.
On P. 4, Table 2 should be read as follows:
Table 2.
Relationship Between USP53 Expression, the Response to Radiotherapy, and Clinicopathological Parameters.
| Characteristics | Patients (n = 40) | USP53 expression positive (n = 10) | USP53 expression negative (n = 30) | P* |
|---|---|---|---|---|
| Age (years) | ||||
| ≦50 | 22 | 6 | 16 | |
| 50 | 18 | 4 | 14 | .503 |
| Tumor diameter | ||||
| <4 | 9 | 3 | 6 | |
| ≧4 | 31 | 7 | 24 | .399 |
| FIGO stage | ||||
| II | 37 | 9 | 28 | |
| III+IV | 3 | 1 | 2 | .589 |
| Tumor shape | ||||
| Endogenous type | 13 | 4 | 9 | |
| Exogenous type | 27 | 6 | 21 | .414 |
| Radiation sensitivity | ||||
| SD | 4 | 3 | 1 | |
| PR | 32 | 7 | 25 | |
| CR | 4 | 0 | 4 | .048 |
Abbreviations: CR, complete response; FIGO, Federation International of Gynecology and Obstetrics; PR, partial response; USP53, ubiquitin-specific protein 53.
P value was estimated by Fisher exact test.
On P. 5 revised Figure 2 caption should be read as follows:
Figure 2. Flow cytometry was performed to detect the effect of knockdown of ubiquitin-specific protein 53 (USP53) in cervical cancer cells on cell cycle progression after radiotherapy. (A) CON group; (B) Si-USP53 group; (C) CON þ 8 Gy group; (D) Si-USP53 þ 8 Gy group; (E) statistical histogram (*P < .05).
On P. 6 revised Figures 4 and 5 captions should be read as follows:
Figure 4. (A) Protein expression of USP53 and DDB2; (B) mRNA expression of USP53 and DDB2 (*P < .05). Abbreviations: USP53, ubiquitin-specific protein 53; DDB2, damage-specific DNA-binding protein 2
Figure 5. (A) Expression of the cell cycle-related proteins cell cycle CHK2; (B) Expression of the CDK1; (*P < .05). Abbreviations: CHK2, checkpoint kinase 2; CDK1, cyclin-dependent kinase 1.