Abstract
Subjective pain score, clinical assessment, 99m technetium joint uptake, infrared thermography, and thermistor skin temperature measurements were evaluated and compared in patients with rheumatoid knee treated with intra-articular hydrocortisone. In 11 patients with definite and classical rheumatoid arthritis, 10 of whom had unilateral knee involvement, the affected knee joints were assessed by the above techniques before and at intervals after treatment of up to 14 days. The anti-inflammatory property of the steroid therapy was shown by all the assessment parameters, values having decreased significantly from the pretreatment values. However, the only parameter still showing a statistically significant decrease on the 14th post-treatment day was 99mTc joint uptake. Correlations were obtained between the two clinical measurements assessed by a physician i.e. pain score and index of joint inflammation. Both of these also correlated with the 99mTc joint uptake but not with skin temperature measurements. Using the clinical assessments as a yardstick, 99mTc joint uptake seemed to provide a useful index of changes in disease activity in the group as a whole. However, skin temperature measurements by infrared thermography and by the thermistor were of considerably less value.
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Selected References
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- Aitken R. C. Measurement of feelings using visual analogue scales. Proc R Soc Med. 1969 Oct;62(10):989–993. doi: 10.1177/003591576906201005. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Boardman P. L., Hart F. D. Clinical measurement of the anti-inflammatory effects of salicylates in rheumatoid arthritis. Br Med J. 1967 Nov 4;4(5574):264–268. doi: 10.1136/bmj.4.5574.264. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Bond M. R., Pilowsky I. Subjective assessment of pain and its relationship to the administration of analgesics in patients with advanced cancer. J Psychosom Res. 1966 Sep;10(2):203–208. doi: 10.1016/0022-3999(66)90064-x. [DOI] [PubMed] [Google Scholar]
- Collins A. J., Ring E. F., Cosh J. A., Bacon P. A. Quantitation of thermography in arthritis using multi-isothermal analysis. I. The thermographic index. Ann Rheum Dis. 1974 Mar;33(2):113–115. doi: 10.1136/ard.33.2.113. [DOI] [PMC free article] [PubMed] [Google Scholar]
- DIAGNOSTIC criteria for rheumatoid arthritis: 1958 revision by a committee of the American Rheumatism Association. Ann Rheum Dis. 1959 Mar;18(1):49–53. [PMC free article] [PubMed] [Google Scholar]
- Dick W. C., Neufeld R. R., Prentice A. G., Woodburn A., Whaley K., Nuki G., Buchanan W. W. Measurement of joint inflammation. A radioisotopic method. Ann Rheum Dis. 1970 Mar;29(2):135–137. doi: 10.1136/ard.29.2.135. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hart F. D., Huskisson E. C. Measurement in rheumatoid arthritis. Lancet. 1972 Jan 1;1(7740):28–30. doi: 10.1016/s0140-6736(72)90015-3. [DOI] [PubMed] [Google Scholar]
- Huskisson E. C., Berry H., Browett J. P., Balme H. W. Measurement of inflammation. II. Comparison of technetium clearance and thermography with standard methods in a clinical trial. Ann Rheum Dis. 1973 Mar;32(2):99–102. doi: 10.1136/ard.32.2.99. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ritchie D. M., Boyle J. A., McInnes J. M., Jasani M. K., Dalakos T. G., Grieveson P., Buchanan W. W. Clinical studies with an articular index for the assessment of joint tenderness in patients with rheumatoid arthritis. Q J Med. 1968 Jul;37(147):393–406. [PubMed] [Google Scholar]
- Shimmins J., Donald M., Kay M., James W. B., Evans A. L. The digitization and analysis of thermographic images. Phys Med Biol. 1977 Jan;22(1):95–97. doi: 10.1088/0031-9155/22/1/013. [DOI] [PubMed] [Google Scholar]