Abstract
Serum C-reactive protein (CRP) and the erythrocyte sedimentation rate (ESR) were compared in 241 patients with rheumatoid arthritis (RA). There was a positive linear correlation between the 2 measurements with a high degree of variability. Neither age nor duration of RA had a detectable influence. The relationship between CRP and ESR was, however, altered by treatment with gold, penicillamine, or high doses of prednisone. It is suggested that serum CRP is the more sensitive measurement, but that CRP and ESR do not have identical clinical significance.
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Selected References
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- Amos R. S., Constable T. J., Crockson R. A., Crockson A. P., McConkey B. Rheumatoid arthritis: relation of serum C-reactive protein and erythrocyte sedimentation rates to radiographic changes. Br Med J. 1977 Jan 22;1(6055):195–197. doi: 10.1136/bmj.1.6055.195. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Amos R. S., Crockson R. A., Crockson A. P., Walsh L., McConkey B. Rheumatoid arthritis: C-reactive protein and erythrocyte sedimentation rate during initial treatment. Br Med J. 1978 May 27;1(6124):1396–1396. doi: 10.1136/bmj.1.6124.1396. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Constable T. J., Crockson R. A., Crockson A. P., McConkey B. Drug treatment of rheumatoid arthritis. A systematic approach. Lancet. 1975 May 24;1(7917):1176–1180. doi: 10.1016/s0140-6736(75)93150-5. [DOI] [PubMed] [Google Scholar]
- McConkey B., Crockson R. A., Crockson A. P. The assessment of rheumatoid arthritis. A study based on measurements of the serum acute-phase reactants. Q J Med. 1972 Apr;41(162):115–125. [PubMed] [Google Scholar]
- McConkey B., Crockson R. A., Crockson A. P., Wilkinson A. R. The effects of some anti-inflammatory drugs on the acute-phase proteins in rheumatoid arthritis. Q J Med. 1973 Oct;42(168):785–791. [PubMed] [Google Scholar]