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. 1980 Apr;39(2):164–167. doi: 10.1136/ard.39.2.164

Local denaturation of collagen fibres during the mechanical rupture of collagenous fibrous tissue.

R J Minns, F S Steven
PMCID: PMC1000503  PMID: 7387220

Abstract

Human extensor tendons of the hand were pulled to rupture, and the torn ends, when observed in the scanning electron microscope, appeared to be knotted, possibly owing to the denaturation of the collagen. This confirmed by fluorimetry assays of both the ruptured ends and the middle unbroken sections of the same tendons. The use of a proteolytic enzyme, trypsin, to remove the denatured material and enhance the repair of organised collagen fibres from both ends is suggested if the ruptured ends have the denatured knotted appearance commonly observed clinically.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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