Abstract
Deep vein thrombophlebitis (DVT) and pulmonary emboli (PE) have been uncommonly reported manifestations of systemic lupus erythematosus (SLE). This may be partly due to their being masked by other more familiar lesions of the lungs and extremities in SLE. We have identified 17 patients with SLE from a population of 180 being followed up prospectively who had 21 attacks of DVT and/or PE. Of the total of 21 episodes the SLE was considered to be active in 14, inactive in 6, and variable in a patient with recurring phlebitis. The incidence of hyperlipidaemia, smoking history, and use of birth control medication or corticosteroids was not higher in these patients. These clinical findings thus constitute additional features of SLE occurring in about 9% of patients and may be significance for morbidity and mortality.
Full text
PDF



Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- ALARCON SEGOVIA D., OSMUNDSON P. J. PERIPHERAL VASCULAR SYNDROMES ASSOCIATED WITH SYSTEMIC LUPUS ERYTHEMATOSUS. Ann Intern Med. 1965 May;62:907–919. doi: 10.7326/0003-4819-62-5-907. [DOI] [PubMed] [Google Scholar]
- ARMAS-CRUZ R., HARNECKER J., DUCACH G., JALIL J., GONZALEZ F. Clinical diagnosis of systemic lupus erythematosus. Am J Med. 1958 Sep;25(3):409–419. doi: 10.1016/0002-9343(58)90080-9. [DOI] [PubMed] [Google Scholar]
- Appel G. B., Williams G. S., Meltzer J. I., Pirani C. L. Renal vein thrombosis, nephrotic syndrome, and systemic lupus erythematosus: an association in four cases. Ann Intern Med. 1976 Sep;85(3):310–317. doi: 10.7326/0003-4819-85-3-310. [DOI] [PubMed] [Google Scholar]
- BOWIE E. J., THOMPSON J. H., Jr, PASCUZZI C. A., OWEN C. A., Jr THROMBOSIS IN SYSTEMIC LUPUS ERYTHEMATOSUS DESPITE CIRCULATING ANTICOAGULANTS. J Lab Clin Med. 1963 Sep;62:416–430. [PubMed] [Google Scholar]
- Gutierrez Millet V., Usera G., Alcazar de la Ossa J. M., Ruilope L. M., Ortuno M. T., Rodicio J. L. Renal vein thrombosis, nephrotic syndrome, and focal lupus glomerulonephritis. Br Med J. 1978 Jan 7;1(6104):24–25. doi: 10.1136/bmj.1.6104.24-a. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hamilton C. R., Jr, Tumulty P. A. Thrombosis of renal veins and inferior vena cava complicating lupus nephritis. JAMA. 1968 Dec 2;206(10):2315–2317. [PubMed] [Google Scholar]
- MOORE J. E., LUTZ W. B. The natural history of systemic lupus erythematosus: an approach to its study through chronic biologic false positive reactors. J Chronic Dis. 1955 Mar;1(3):297–316. doi: 10.1016/0021-9681(55)90039-4. [DOI] [PubMed] [Google Scholar]
- Peck B., Hoffman G. S., Franck W. A. Thrombophlebitis in systemic lupus erythematosus. JAMA. 1978 Oct 13;240(16):1728–1730. [PubMed] [Google Scholar]