Skip to main content
NCBI home page
Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
. 1981 Feb;40(1):37–41. doi: 10.1136/ard.40.1.37

Effect of aspirin treatment on chondromalacia patellae.

G Bentley, I J Leslie, D Fischer
PMCID: PMC1000652  PMID: 7008711

Abstract

Twenty-nine patients (21 females and 8 males) with chondromalacia patellae diagnosed by arthroscopy were randomly allocated to receive aspirin or placebo for 3 months. Clinical and arthroscopic examination after 3 months showed no significant change in symptoms, signs, or macroscopic appearances in either group. Surgical treatment was performed in 14 patients for deteriorating symptoms.

Full text

PDF
37

Images in this article

39Image
on p.39

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ali S. Y. The degradation of cartilage matrix by an intracellular protease. Biochem J. 1964 Dec;93(3):611–618. doi: 10.1042/bj0930611. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Bentley G. Chondromalacia patellae. J Bone Joint Surg Am. 1970 Mar;52(2):221–232. [PubMed] [Google Scholar]
  3. Bentley G. The surgical treatment of chondromalacia patellae. J Bone Joint Surg Br. 1978 Feb;60(1):74–81. doi: 10.1302/0301-620X.60B1.627583. [DOI] [PubMed] [Google Scholar]
  4. COLLINS D. H., McELLIGOTT T. F. Sulphate (35SO4) uptake by chondrocytes in relation to histological changes in osteoarthritic human articular cartilage. Ann Rheum Dis. 1960 Dec;19:318–330. doi: 10.1136/ard.19.4.318. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Chrisman O. D. Biochemical aspects of degenerative joint disease. Clin Orthop Relat Res. 1969 May-Jun;64:77–86. [PubMed] [Google Scholar]
  6. Chrisman O. D., Snook G. A. Studies on the protective effect of aspirin against degeneration of human articular cartilage. A preliminary report. Clin Orthop Relat Res. 1968 Jan-Feb;56:77–82. [PubMed] [Google Scholar]
  7. Chrisman O. D., Snook G. A., Wilson T. C. The protective effect of aspirin against degeneration of human articular cartilage. Clin Orthop Relat Res. 1972 May;84:193–196. doi: 10.1097/00003086-197205000-00031. [DOI] [PubMed] [Google Scholar]
  8. DUTHIE H. L., HUTCHINSON J. R. The results of partial and total excision of the patella. J Bone Joint Surg Br. 1958 Feb;40-B(1):75–81. doi: 10.1302/0301-620X.40B1.75. [DOI] [PubMed] [Google Scholar]
  9. Dingle J. T. Heberden oration 1978. Recent studies on the control of joint damage: the contribution of the Strangeways Research Laboratory. Ann Rheum Dis. 1979 Jun;38(3):201–214. doi: 10.1136/ard.38.3.201. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Evans C. D. Some problems in rehabilitation in the services. Chondromalacia patellae. Proc R Soc Med. 1966 Jul;59(7):626–627. [PMC free article] [PubMed] [Google Scholar]
  11. FESSEL J. M., CHRISMAN O. D. ENZYMATIC DEGRADATION OF CHONDROMUCOPROTEIN BY CELL-FREE EXTRACTS OF HUMAN CARTILAGE. Arthritis Rheum. 1964 Aug;7:398–405. doi: 10.1002/art.1780070406. [DOI] [PubMed] [Google Scholar]
  12. Leslie I. J., Bentley G. Arthroscopy in the diagnosis of chondromalacia patellae. Ann Rheum Dis. 1978 Dec;37(6):540–547. doi: 10.1136/ard.37.6.540. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Mankin H. J. The effect of aging on articular cartilage. Bull N Y Acad Med. 1968 May;44(5):545–552. [PMC free article] [PubMed] [Google Scholar]
  14. OUTERBRIDGE R. E. The etiology of chondromalacia patellae. J Bone Joint Surg Br. 1961 Nov;43-B:752–757. doi: 10.1302/0301-620X.43B4.752. [DOI] [PubMed] [Google Scholar]
  15. Repo R. U., Mitchell N. Collagen synthesis in mature articular cartilage of the rabbit. J Bone Joint Surg Br. 1971 Aug;53(3):541–548. [PubMed] [Google Scholar]
  16. Robinson A. R., Darracott J. Chondromalacia patellae. A survey conducted at the Army Medical Rehabilitation Unit, Chester. Ann Phys Med. 1970 May;10(6):286–290. doi: 10.1093/rheumatology/x.6.286. [DOI] [PubMed] [Google Scholar]
  17. Simmons D. P., Chrisman O. D. Salicylate inhibition of cartilage degeneration. Arthritis Rheum. 1965 Oct;8(5):960–969. doi: 10.1002/art.1780080506. [DOI] [PubMed] [Google Scholar]
  18. WILES P., ANDREWS P. S., DEVAS M. B. Chondromalacia of the patella. J Bone Joint Surg Br. 1956 Feb;38-B(1):95–113. doi: 10.1302/0301-620X.38B1.95. [DOI] [PubMed] [Google Scholar]

Articles from Annals of the Rheumatic Diseases are provided here courtesy of BMJ Publishing Group

RESOURCES