Skip to main content
Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
. 1981 Jun;40(3):272–275. doi: 10.1136/ard.40.3.272

Plasma viscosity--a new appraisal of its use as an index of disease activity in rheumatoid arthritis.

M E Pickup, J S Dixon, C Hallett, H A Bird, V Wright
PMCID: PMC1000761  PMID: 7247471

Abstract

The suitability of the plasma viscosity (PV) test has been examined in relation to the more commonly used erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) estimations as a diagnostic aid in 120 outpatients with rheumatoid arthritis (RA) and as an index of improvement during subsequent specific antirheumatic drug treatment (60 outpatients). Correlation data based on 7 clinical variables suggest that PV estimations are at least as reliable as ESR and CRP in terms of diagnosis and as indices of improvement. The methodological advantages offered by the PV test lend support to its application in RA.

Full text

PDF
272

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Amos R. S., Constable T. J., Crockson R. A., Crockson A. P., McConkey B. Rheumatoid arthritis: relation of serum C-reactive protein and erythrocyte sedimentation rates to radiographic changes. Br Med J. 1977 Jan 22;1(6055):195–197. doi: 10.1136/bmj.1.6055.195. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Bird H. A., Dixon J. S., Pickup M. E., Lee M. R., Wright V. A biochemical comparison of alclofenac and D-penicillamine in rheumatoid arthritis. Ann Rheum Dis. 1980 Jun;39(3):281–284. doi: 10.1136/ard.39.3.281. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. COWAN I. C., HARKNESS J. The plasma viscosity in rheumatic diseases. Br Med J. 1947 Nov 1;2(4530):686–688. doi: 10.1136/bmj.2.4530.686. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Dixon J. S., Pickup M. E., Lowe J. R., Hallett C., Lee M. R., Wright V. Discriminatory indices of response of patients with rheumatoid arthritis treated with D-penicillamine. Ann Rheum Dis. 1980 Aug;39(4):301–311. doi: 10.1136/ard.39.4.301. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. FREEDMAN A. Chloroquine and rheumatoid arthritis; a short-term controlled trial. Ann Rheum Dis. 1956 Sep;15(3):251–257. doi: 10.1136/ard.15.3.251. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Harkness J. The viscosity of human blood plasma; its measurement in health and disease. Biorheology. 1971 Dec;8(3):171–193. doi: 10.3233/bir-1971-83-408. [DOI] [PubMed] [Google Scholar]
  7. Mancini G., Carbonara A. O., Heremans J. F. Immunochemical quantitation of antigens by single radial immunodiffusion. Immunochemistry. 1965 Sep;2(3):235–254. doi: 10.1016/0019-2791(65)90004-2. [DOI] [PubMed] [Google Scholar]
  8. Rhind V. M., Bird H. A., Wright V. A comparison of clinical assessments of disease activity in rheumatoid arthritis. Ann Rheum Dis. 1980 Apr;39(2):135–137. doi: 10.1136/ard.39.2.135. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Walsh L., Davies P., McConkey B. Relationship between erythrocyte sedimentation rate and serum C-reactive protein in rheumatoid arthritis. Ann Rheum Dis. 1979 Aug;38(4):362–363. doi: 10.1136/ard.38.4.362. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Annals of the Rheumatic Diseases are provided here courtesy of BMJ Publishing Group

RESOURCES