Skip to main content
Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
. 1981 Oct;40(5):489–492. doi: 10.1136/ard.40.5.489

Lactate UV-system: a rapid method for diagnosis of septic arthritis.

A R Behn, J A Mathews, I Phillips
PMCID: PMC1000786  PMID: 7305472

Abstract

The concentration of lactic acid in synovial fluid was estimated in 43 specimens from patients with an acute monoarthritis by a simple enzyme method. In 9 patients with 10 episodes of septic arthritis concentrations of synovial fluid lactic acid were significantly higher (mean 10.8 mmol/l) than in 33 patients with nonseptic effusions (mean 3.1 mmol/l). With this method concentrations of synovial fluid lactic acid provide a rapid diagnostic guide in the separation of septic from nonseptic arthritis.

Full text

PDF
489

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Brook I., Reza M. J., Bricknell K. S., Bluestone R., Finegold S. M. Synovial fluid lactic acid. A diagnostic aid in septic arthritis. Arthritis Rheum. 1978 Sep-Oct;21(7):774–779. doi: 10.1002/art.1780210706. [DOI] [PubMed] [Google Scholar]
  2. Brooks J. B., Kellogg D. S., Alley C. C., Short H. B., Handsfield H. H., Huff B. Gas chromatography as a potential means of diagnosing arthritis. I. Differentiation between staphylococcal, streptococcal, gonococcal, and traumatic arthritis. J Infect Dis. 1974 Jun;129(6):660–668. doi: 10.1093/infdis/129.6.660. [DOI] [PubMed] [Google Scholar]
  3. Buckingham R. B., Castor C. W. The effect of bacterial products on synovial fibroblast function: hypermetabolic changes induced by endotoxin. J Clin Invest. 1972 May;51(5):1186–1194. doi: 10.1172/JCI106912. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. COHN Z. A., MORSE S. I. Functional and metabolic properties of polymorphonuclear leucocytes. II. The influence of a lipopolysaccharide endotoxin. J Exp Med. 1960 May 1;111:689–704. doi: 10.1084/jem.111.5.689. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Goldenberg D. L., Cohen A. S. Acute infectious arthritis. A review of patients with nongonococcal joint infections (with emphasis on therapy and prognosis). Am J Med. 1976 Mar;60(3):369–377. doi: 10.1016/0002-9343(76)90753-1. [DOI] [PubMed] [Google Scholar]
  6. Lund-Olesen K. Oxygen tension in synovial fluids. Arthritis Rheum. 1970 Nov-Dec;13(6):769–776. doi: 10.1002/art.1780130606. [DOI] [PubMed] [Google Scholar]
  7. Newman J. H. Review of septic arthritis throughout the antibiotic era. Ann Rheum Dis. 1976 Jun;35(3):198–205. doi: 10.1136/ard.35.3.198. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Treuhaft P. S., MCCarty D. J. Synovial fluid pH, lactate, oxygen and carbon dioxide partial pressure in various joint diseases. Arthritis Rheum. 1971 Jul-Aug;14(4):475–484. doi: 10.1002/art.1780140407. [DOI] [PubMed] [Google Scholar]

Articles from Annals of the Rheumatic Diseases are provided here courtesy of BMJ Publishing Group

RESOURCES