Skip to main content
Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
. 1981 Oct;40(5):509–512. doi: 10.1136/ard.40.5.509

Neonatal Behçet's syndrome in an infant of a mother with the disease.

A G Fam, K A Siminovitch, S Carette, L From
PMCID: PMC1000792  PMID: 7305476

Abstract

Behçet's disease is reported in a newborn infant of a mother with the disease. The mother had recurrent orogenital ulcers, pustulonecrotic skin lesions, arthritis, thrombophlebitis, and colonic ulcers. Shortly after birth the infant presented with transient orogenital ulcerations and pustular cutaneous lesions. On healing, depressed scars developed which were very similar to those of the mother. The finding of circulating immune complexes in the mother's serum gives some support to the hypothesis that the infant's transient illness was caused by transplacental passage of maternal antibodies.

Full text

PDF
509

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Abdel-Aziz A. H., Fairburn E. A. Familial Behcet's syndrome. Cutis. 1978 May;21(5):649–652. [PubMed] [Google Scholar]
  2. Berman L., Trappler B., Jenkins T. Behçet's syndrome: a family study and the elucidation of a genetic role. Ann Rheum Dis. 1979 Apr;38(2):118–121. doi: 10.1136/ard.38.2.118. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Brouet J. C., Clauvel J. P., Danon F., Klein M., Seligmann M. Biologic and clinical significance of cryoglobulins. A report of 86 cases. Am J Med. 1974 Nov;57(5):775–788. doi: 10.1016/0002-9343(74)90852-3. [DOI] [PubMed] [Google Scholar]
  4. Chajek T., Fainaru M. Behçet's disease. Report of 41 cases and a review of the literature. Medicine (Baltimore) 1975 May;54(3):179–196. doi: 10.1097/00005792-197505000-00001. [DOI] [PubMed] [Google Scholar]
  5. Fadli M. E., Youssef M. M. Neuro-Behçet's syndrome in the United Arab Republic. Eur Neurol. 1973;9(2):76–89. doi: 10.1159/000114215. [DOI] [PubMed] [Google Scholar]
  6. Fenech F. F., Soler N. G. Hyperkalemic periodic paralysis starting at age 48. Br Med J. 1968 May 25;2(5603):472–473. doi: 10.1136/bmj.2.5603.472. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Gamble C. N., Wiesner K. B., Shapiro R. F., Boyer W. J. The immune complex pathogenesis of glomerulonephritis and pulmonary vasculitis in Behçet's disease. Am J Med. 1979 Jun;66(6):1031–1039. doi: 10.1016/0002-9343(79)90461-3. [DOI] [PubMed] [Google Scholar]
  8. Goolamali S. K., Comaish J. S., Hassanyeh F., Stephens A. Familial Behçet's syndrome. Br J Dermatol. 1976 Dec;95(6):637–642. doi: 10.1111/j.1365-2133.1976.tb07037.x. [DOI] [PubMed] [Google Scholar]
  9. Hurt W. G., Cooke C. L., Jordan W. P., Bullock J. P., Jr, Rodriguez G. E. Behçet's syndrome associated with pregnancy. Obstet Gynecol. 1979 Mar;53(3 Suppl):31S–33S. [PubMed] [Google Scholar]
  10. JACKSON R. DISCOID LUPUS IN A NEWBORN INFANT OF A MOTHER WITH LUPUS ERYTHEMATOSUS. Pediatrics. 1964 Mar;33:425–430. [PubMed] [Google Scholar]
  11. Keesey J., Lindstrom J., Cokely H. Anti-acetylcholine receptor antibody in neonatal myasthenia gravis. N Engl J Med. 1977 Jan 6;296(1):55–55. doi: 10.1056/NEJM197701062960125. [DOI] [PubMed] [Google Scholar]
  12. Madkour M., Kudwah A. Behçet's disease. Br Med J. 1978 Dec 23;2(6154):1786–1786. doi: 10.1136/bmj.2.6154.1786-a. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Mason R. M., Barnes C. G. Behçet's syndrome with arthritis. Ann Rheum Dis. 1969 Mar;28(2):95–103. doi: 10.1136/ard.28.2.95. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Nydegger U. E., Lambert P. H., Gerber H., Miescher P. A. Circulating immune complexes in the serum in systemic lupus erythematosus and in carriers of hepatitis B antigen. Quantitation by binding to radiolabeled C1q. J Clin Invest. 1974 Aug;54(2):297–309. doi: 10.1172/JCI107765. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Ono S., Nakayama E., Sugiura S., Itakura K., Aoki K. Specific histocompatibility antigens associated with Behçet's disease. Am J Ophthalmol. 1975 Oct;80(4):636–641. doi: 10.1016/0002-9394(75)90394-3. [DOI] [PubMed] [Google Scholar]
  16. Oshima Y., Shimizu T., Yokohari R., Matsumoto T., Kano K., Kagami T., Nagaya H. Clinical Studies on Behçet's Syndrome. Ann Rheum Dis. 1963 Jan;22(1):36–45. doi: 10.1136/ard.22.1.36. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Prchal J. T., Blakely J. Letter: Granulocyte platelet rosettes. N Engl J Med. 1973 Nov 22;289(21):1146–1146. doi: 10.1056/NEJM197311222892117. [DOI] [PubMed] [Google Scholar]
  18. SEZER N. Further investigations on the virus of Behçet's disease. Am J Ophthalmol. 1956 Jan;41(1):41–55. [PubMed] [Google Scholar]
  19. Scarlett J. A., Kistner M. L., Yang L. C. Behçet's syndrome. Report of a case associated with pericardial effusion and cryoglobulinemia treated with indomethacin. Am J Med. 1979 Jan;66(1):146–148. doi: 10.1016/0002-9343(79)90506-0. [DOI] [PubMed] [Google Scholar]
  20. Shimizu T., Ehrlich G. E., Inaba G., Hayashi K. Behçet disease (Behçet syndrome). Semin Arthritis Rheum. 1979 May;8(4):223–260. doi: 10.1016/0049-0172(79)90004-0. [DOI] [PubMed] [Google Scholar]

Articles from Annals of the Rheumatic Diseases are provided here courtesy of BMJ Publishing Group

RESOURCES