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Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
. 1982 Dec;41(6):579–586. doi: 10.1136/ard.41.6.579

Histopathology of the synovial membrane of peripheral joints in ankylosing spondylitis.

P A Revell, V Mayston
PMCID: PMC1000988  PMID: 6756321

Abstract

The histological features of the synovial membrane of peripheral joints in ankylosing spondylitis are similar to those seen in rheumatoid arthritis. There is intimal cell hyperplasia, a diffuse lymphocyte and plasma cell infiltrate, and formation of lymphoid follicles. Peroxidase-antiperoxidase staining shows the presence of IgG-, IgA-, and IgM-containing plasma cells in ankylosing spondylitis. The percentage of IgM-containing cells is significantly lower in ankylosing spondylitis than in rheumatoid arthritis.

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Selected References

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