Abstract
To assess the antirheumatic activity of zinc sulphate, 27 patients with active rheumatoid arthritis took part in a 6-month, randomised, double-blind, between-group trial of oral zinc sulphate versus placebo. Twelve patients on zinc and 9 on placebo completed the trial, but no significant antirheumatic activity of zinc sulphate was demonstrated.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- Balogh Z., El-Ghobarey A. F., Fell G. S., Brown D. H., Dunlop J., Dick W. C. Plasma zinc and its relationship to clinical symptoms and drug treatment in rheumatoid arthritis. Ann Rheum Dis. 1980 Aug;39(4):329–332. doi: 10.1136/ard.39.4.329. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Clemmensen O. J., Siggaard-Andersen J., Worm A. M., Stahl D., Frost F., Bloch I. Psoriatic arthritis treated with oral zinc sulphate. Br J Dermatol. 1980 Oct;103(4):411–415. doi: 10.1111/j.1365-2133.1980.tb07264.x. [DOI] [PubMed] [Google Scholar]
- Job C., Menkes C. J., Delbarre F. Zinc sulfate in the treatment of rheumatoid arthritis. Arthritis Rheum. 1980 Dec;23(12):1408–1409. doi: 10.1002/art.1780231221. [DOI] [PubMed] [Google Scholar]
- Johnstone J. J., Bitensky L., Cashman B., Chayen J. The effect of zinc on alkaline phosphatase activity in rheumatoid synovial tissue. Ann Rheum Dis. 1978 Dec;37(6):552–556. doi: 10.1136/ard.37.6.552. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kennedy A. C., Fell G. S., Rooney P. J., Stevens W. H., Dick W. C., Buchanan W. W. Zinc: its relationship to osteoporosis in rheumatoid arthritis. Scand J Rheumatol. 1975;4(4):243–245. doi: 10.3109/03009747509165264. [DOI] [PubMed] [Google Scholar]
- Simkin P. A. Oral zinc sulphate in rheumatoid arthritis. Lancet. 1976 Sep 11;2(7985):539–542. doi: 10.1016/s0140-6736(76)91793-1. [DOI] [PubMed] [Google Scholar]