Abstract
Using a quantitative method, scintigraphy of SI joints was performed by means of 99m technetium pyrophosphate in 21 patients with definite ankylosing spondylitis, in 17 control patients, and in 26 patients 'at risk', i.e. patients with complaints of back pain of the inflammatory type where on clinical grounds there was a possibility of sacroiliitis developing but with normal x-ray findings of the SI joints. Radioisotope uptake was higher in the ankylosing spondylitis group than in the other two groups, although the difference was not statistically significant with regard to the group 'at risk'. The high variance in the three groups considerably reduces the diagnostic value of the examination. In the ankylosing spondylitis group no correlation was found between radioisotope uptake and age, duration of disease, erythrocyte sedimentation rate, or radiological stage of scaroiliitis. Since the specificity and sensitivity of scintiscanning are lower than that of clinical and radiological diagnosis of the disease, we conclude that scintigraphy is not very helpful in the early diagnosis of sacroiliitis, at least by the techniques used here.
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Selected References
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- Lentle B. C., Russell A. S., Percy J. S., Jackson F. I. The scintigraphic investigation of sacroiliac disease. J Nucl Med. 1977 Jun;18(6):529–533. [PubMed] [Google Scholar]
- Macrae I. F., Wright V. Measurement of back movement. Ann Rheum Dis. 1969 Nov;28(6):584–589. doi: 10.1136/ard.28.6.584. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Merrick M. V. Review article-Bone scanning. Br J Radiol. 1975 May;48(569):327–351. doi: 10.1259/0007-1285-48-569-327. [DOI] [PubMed] [Google Scholar]
- Moll J. M., Wright V. An objective clinical study of chest expansion. Ann Rheum Dis. 1972 Jan;31(1):1–8. doi: 10.1136/ard.31.1.1. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Moll J. M., Wright V. New York clinical criteria for ankylosing spondylitis. A statistical evaluation. Ann Rheum Dis. 1973 Jul;32(4):354–363. doi: 10.1136/ard.32.4.354. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Moll J. M., Wright V. Normal range of spinal mobility. An objective clinical study. Ann Rheum Dis. 1971 Jul;30(4):381–386. doi: 10.1136/ard.30.4.381. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Subramanian G., McAfee J. G. A new complex of 99mTc for skeletal imaging. Radiology. 1971 Apr;99(1):192–196. doi: 10.1148/99.1.192. [DOI] [PubMed] [Google Scholar]
- Van Laere M., Veys E. M., Mielants H. Strontium 87m scanning of the sacroiliac joints in ankylosing spondylitis. Ann Rheum Dis. 1972 May;31(3):201–206. doi: 10.1136/ard.31.3.201. [DOI] [PMC free article] [PubMed] [Google Scholar]
- WOOD H. G. The metabolism of formate by animals. Harvey Lect. 1949 1950;Series 45:127–148. [PubMed] [Google Scholar]