CDK4 is an essential insulin effector in adipocytes

Original citation: J Clin Invest. 2016;126(1):335–348. https://doi.org/10.1172/JCI81480

Citation for this retraction: J Clin Invest. 2023;133(6):170315. https://doi.org/10.1172/JCI170315

At the request of the corresponding author, the JCI is retracting this article. The authors became aware that the genotype of the mice described as Cdk4^neo/neo Rip-Cre was incorrect. The correct mouse genotype was Cdk4^neo/neo Rip-Cdk4^R24C. The model used transgenically expresses the Cdk4^R24C allele under the control of the rat insulin promoter (Rip-Cdk4^R24C) rather than expressing Cdk4^R24C in the Cdk4 locus as described in the article. Due to this unintentional error, the corresponding author requested retraction.

Version 1. 03/15/2023

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