Abstract
The usefulness of anti-inflammatory drugs in rheumatoid arthritis (RA) is beyond dispute. The role of simple analgesics is less clear and has been disputed. A survey of 21 rheumatologists indicated that a majority sometimes supplemented anti-inflammatory treatment of RA with simple analgesics. A random sample of 120 RA patients treated by the same doctors revealed that 47% ranked pain relief as the most desirable objective of their treatment and 54% were taking analgesics regularly. Of those receiving analgesics as well as non-steroidal anti-inflammatory drugs 48% considered the former to be the more effective preparations. Almost half the patients on analgesics were taking drugs without the knowledge of the rheumatologists, who may have underestimated their patients' desire for pain relief.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- Brooks P. M., Dougan M. A., Mugford S., Meffin E. Comparative effectiveness of 5 analgesics in patients with rheumatoid arthritis and osteoarthritis. J Rheumatol. 1982 Sep-Oct;9(5):723–726. [PubMed] [Google Scholar]
- Constable T. J., Crockson R. A., Crockson A. P., McConkey B. Drug treatment of rheumatoid arthritis. A systematic approach. Lancet. 1975 May 24;1(7917):1176–1180. doi: 10.1016/s0140-6736(75)93150-5. [DOI] [PubMed] [Google Scholar]
- Hardin J. G., Jr, Kirk K. A. Comparative effectiveness of five analgesics for the pain of rheumatoid synovitis. J Rheumatol. 1979 Jul-Aug;6(4):405–412. [PubMed] [Google Scholar]
- Huskisson E. C. Simple analgesics for arthritis. Br Med J. 1974 Oct 26;4(5938):196–200. doi: 10.1136/bmj.4.5938.196. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lee P., Ahola S. J., Grennan D., Brooks P., Buchanan W. W. Observations on drug prescribing in rheumatoid arthritis. Br Med J. 1974 Mar 9;1(5905):424–426. doi: 10.1136/bmj.1.5905.424. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Nuki G., Downie W. W., Dick W. C., Whaley K., Spooner J. B., Darby-Dowman M. A., Buchanan W. W. Clinical trial of pentazocine in rheumatoid arthritis. Observations on the value of potent analgesics and placebos. Ann Rheum Dis. 1973 Sep;32(5):436–443. doi: 10.1136/ard.32.5.436. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Nuki G. Non-steroidal analgesic and anti-inflammatory agents. Br Med J (Clin Res Ed) 1983 Jul 2;287(6384):39–43. doi: 10.1136/bmj.287.6384.39. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ritchie D. M., Boyle J. A., McInnes J. M., Jasani M. K., Dalakos T. G., Grieveson P., Buchanan W. W. Clinical studies with an articular index for the assessment of joint tenderness in patients with rheumatoid arthritis. Q J Med. 1968 Jul;37(147):393–406. [PubMed] [Google Scholar]