Skip to main content
NCBI home page
Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
. 1985 May;44(5):345–348. doi: 10.1136/ard.44.5.345

Adult-onset Still's disease complicated by hypercalcaemia: possible relationship with rapidly destructive polyarthritis.

J M Wouters, P G Froeling, L B van de Putte
PMCID: PMC1001644  PMID: 4004364

Abstract

A 34-year-old man with adult-onset Still's disease developed a striking hypercalcaemia during a rapidly destructive polyarthritis with extensive osteoporosis. The hypercalcaemia seemed to be primarily caused by inflammation-induced bone resorption. On prednisone the polyarthritis went into remission and the plasma calcium levels became normal. Other remarkable features in this case were a subluxation of the atlantoaxial joint, a brain-stem haemorrhage, transient hyperuricaemia and hyperuricosuria, and urolithiasis.

Full text

PDF
345

Images in this article

346Image
on p.346

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bramble M. G., Blake D. R., White T., Sly J., Kerr D. N. Ionised calcium in rheumatoid arthritis: effect of non-steroidal anti-inflammatory drugs. Br Med J. 1980 Sep 27;281(6244):840–841. doi: 10.1136/bmj.281.6244.840. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Bujak J. S., Aptekar R. G., Decker J. L., Wolff S. M. Juvenile rheumatoid arthritis presenting in the adult as fever of unknown origin. Medicine (Baltimore) 1973 Sep;52(5):431–444. doi: 10.1097/00005792-197309000-00007. [DOI] [PubMed] [Google Scholar]
  3. Bywaters E. G. Still's disease in the adult. Ann Rheum Dis. 1971 Mar;30(2):121–133. doi: 10.1136/ard.30.2.121. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Claus-Walker J., Carter R. E., Compos R. J., Spencer W. A. Hypercalcemia in early traumatic quadriplegia. J Chronic Dis. 1975 Feb;28(2):81–90. doi: 10.1016/0021-9681(75)90064-8. [DOI] [PubMed] [Google Scholar]
  5. Esdaile J. M., Tannenbaum H., Hawkins D. Adult Still's disease. Am J Med. 1980 Jun;68(6):825–830. doi: 10.1016/0002-9343(80)90201-6. [DOI] [PubMed] [Google Scholar]
  6. Kantrowitz F., Robinson D. R., McGuire M. B., Levine L. Corticosteroids inhibit prostaglandin production by rheumatiod synovia. Nature. 1975 Dec 25;258(5537):737–739. doi: 10.1038/258737a0. [DOI] [PubMed] [Google Scholar]
  7. Kennedy A. C., Allam R. F., Rooney P. J., Watson M. E., Fairney A., Buchanan K. D., Hillyard C. J. Hypercalcaemia in rheumatoid arthritis: investigation of its causes and implications. Ann Rheum Dis. 1979 Oct;38(5):401–412. doi: 10.1136/ard.38.5.401. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Robinson D. R., Tashjian A. H., Jr, Levine L. Prostaglandin-stimulated bone resorption by rheumatoid synovia. A possible mechanism for bone destruction in rheumatoid arthritis. J Clin Invest. 1975 Nov;56(5):1181–1188. doi: 10.1172/JCI108195. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Scott D. L., Farr M., Hawkins C. F., Wilkinson R., Bold A. M. Serum calcium levels in rheumatoid arthritis. Ann Rheum Dis. 1981 Dec;40(6):580–583. doi: 10.1136/ard.40.6.580. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Annals of the Rheumatic Diseases are provided here courtesy of BMJ Publishing Group

RESOURCES