Skip to main content
NCBI home page
Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
. 1985 Sep;44(9):580–584. doi: 10.1136/ard.44.9.580

Bone turnover in early rheumatoid arthritis. 2. Longitudinal bone density studies.

P N Sambrook, B M Ansell, S Foster, J M Gumpel, R Hesp, J Reeve
PMCID: PMC1001713  PMID: 3876077

Abstract

Serial measurements of bone mineral in 17 ambulant female patients with rheumatoid arthritis (RA) of recent onset and 19 age matched female controls were made in the radius by computed tomography and in the vertebrae by dual photon absorptiometry. Loss of trabecular bone from the distal radius was more rapid in RA (p = 0.0014), but there was no difference in the rate of loss of bone mineral from the radial midshaft or lumbar spine compared with the controls. This study is consistent with the hypothesis that the predominant form of bone loss early in the disease is the vicinity of affected joints.

Full text

PDF
580

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Als O. S., Christiansen C., Hellesen C. Prevalence of decreased bone mass in rheumatoid arthritis. Relation to anti-inflammatory treatment. Clin Rheumatol. 1984 Jun;3(2):201–208. doi: 10.1007/BF02030755. [DOI] [PubMed] [Google Scholar]
  2. BYWATERS E. G. The early radiological signs of rheumatoid arthritis. Bull Rheum Dis. 1960 Nov;11:231–234. [PubMed] [Google Scholar]
  3. Bjelle A. O., Nilsson B. E. Osteoporosis in rheumatoid arthritis. Calcif Tissue Res. 1970;5(4):327–332. doi: 10.1007/BF02017562. [DOI] [PubMed] [Google Scholar]
  4. Castillo B. A., el Sallab R. A., Scott J. T. Physical activity, cystic erosions, and osteoporosis in rheumatoid arthritis. Ann Rheum Dis. 1965 Nov;24(6):522–527. doi: 10.1136/ard.24.6.522. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Christiansen C., Rodbro P. Skeletal status in patients with rheumatoid arthritis. Acta Med Scand. 1975 Dec;198(6):453–454. doi: 10.1111/j.0954-6820.1975.tb19574.x. [DOI] [PubMed] [Google Scholar]
  6. Cohn S. H. Techniques for determining the efficacy of treatment of osteoporosis. Calcif Tissue Int. 1982 Sep;34(5):433–438. doi: 10.1007/BF02411281. [DOI] [PubMed] [Google Scholar]
  7. DIAGNOSTIC criteria for rheumatoid arthritis: 1958 revision by a committee of the American Rheumatism Association. Ann Rheum Dis. 1959 Mar;18(1):49–53. [PMC free article] [PubMed] [Google Scholar]
  8. Elsasser U., Reeve J. Bone density measurement with computed tomography. Br Med Bull. 1980 Sep;36(3):293–296. doi: 10.1093/oxfordjournals.bmb.a071656. [DOI] [PubMed] [Google Scholar]
  9. Hancock D. A., Asiedu-Offei S., Atkinson P. J., Reed G. W., Wright V. Femoral bone mass in patients with rheumatoid arthritis and osteoarthrosis. Rheumatol Rehabil. 1978 May;17(2):65–71. doi: 10.1093/rheumatology/17.2.65. [DOI] [PubMed] [Google Scholar]
  10. Kannel W. B., Sorlie P. Some health benefits of physical activity. The Framingham Study. Arch Intern Med. 1979 Aug;139(8):857–861. [PubMed] [Google Scholar]
  11. Kennedy A. C., Smith D. A., Anton H. C., Buchanan W. W. Generalised and localised bone loss in patients with rheumatoid arthritis. Scand J Rheumatol. 1975;4(4):209–215. doi: 10.3109/03009747509165258. [DOI] [PubMed] [Google Scholar]
  12. Krølner B., Pors Nielsen S. Measurement of bone mineral content (BMC) of the lumbar spine, I. Theory and application of a new two-dimensional dual-photon attenuation method. Scand J Clin Lab Invest. 1980;40(7):653–663. doi: 10.1080/00365518009091978. [DOI] [PubMed] [Google Scholar]
  13. Lereim P., Goldie I. F. Relationship between morphologic features and hardness of the subchondral bone of the medial tibial condyle in the normal state and in osteoarthritis and rheumatoid arthritis. Arch Orthop Unfallchir. 1975;81(1):1–11. doi: 10.1007/BF00417022. [DOI] [PubMed] [Google Scholar]
  14. Mazess R. B. Errors in measuring trabecular bone by computed tomography due to marrow and bone composition. Calcif Tissue Int. 1983;35(2):148–152. doi: 10.1007/BF02405022. [DOI] [PubMed] [Google Scholar]
  15. Mueller M. N., Jurist J. M. Skeletal status in rheumatoid arthritis. A preliminary report. Arthritis Rheum. 1973 Jan-Feb;16(1):66–70. doi: 10.1002/art.1780160110. [DOI] [PubMed] [Google Scholar]
  16. Oka M., Rekonen A., Kuikka J., Anttinen J. Bone mineral density in rheumatoid arthritis measured by the gamma transmission method. Scand J Rheumatol. 1975;4(1):28–32. [PubMed] [Google Scholar]
  17. Reid D. M., Kennedy N. S., Smith M. A., Tothill P., Nuki G. Total body calcium in rheumatoid arthritis: effects of disease activity and corticosteroid treatment. Br Med J (Clin Res Ed) 1982 Jul 31;285(6338):330–332. doi: 10.1136/bmj.285.6338.330. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Ritchie D. M., Boyle J. A., McInnes J. M., Jasani M. K., Dalakos T. G., Grieveson P., Buchanan W. W. Clinical studies with an articular index for the assessment of joint tenderness in patients with rheumatoid arthritis. Q J Med. 1968 Jul;37(147):393–406. [PubMed] [Google Scholar]
  19. Rüegsegger P., Stebler B., Dambacher M. Quantitative computed tomography of bone. Mayo Clin Proc. 1982 Jul;57 (Suppl):96–103. [PubMed] [Google Scholar]
  20. Saville P. D., Kharmosh O. Osteoporosis of rheumatoid arthritis: influence of age, sex and corticosteroids. Arthritis Rheum. 1967 Oct;10(5):423–430. doi: 10.1002/art.1780100504. [DOI] [PubMed] [Google Scholar]
  21. Schlesselman J. J. Planning a longitudinal study. II. Frequency of measurement and study duration. J Chronic Dis. 1973 Sep;26(9):561–570. doi: 10.1016/0021-9681(73)90061-1. [DOI] [PubMed] [Google Scholar]
  22. Virtama P., Helelä T., Kalliomäki J. L. Osteoporosis in rheumatoid arthritis. A follow-up study. Acta Rheumatol Scand. 1968;14(4):276–284. doi: 10.3109/rhe1.1968.14.issue-1-4.30. [DOI] [PubMed] [Google Scholar]

Articles from Annals of the Rheumatic Diseases are provided here courtesy of BMJ Publishing Group

RESOURCES