Abstract
A patient with systemic lupus erythematosus was first diagnosed after she had developed the Budd-Chiari syndrome. We believe that the Budd-Chiari syndrome was part of her tendency for thrombosis, induced by the presence of a lupus anticoagulant. The association between enhanced thrombosis and the lupus anticoagulant is discussed, and the need for prompt recognition and administration of anticoagulant therapy is emphasised.
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Selected References
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- BOWIE E. J., THOMPSON J. H., Jr, PASCUZZI C. A., OWEN C. A., Jr THROMBOSIS IN SYSTEMIC LUPUS ERYTHEMATOSUS DESPITE CIRCULATING ANTICOAGULANTS. J Lab Clin Med. 1963 Sep;62:416–430. [PubMed] [Google Scholar]
- Boey M. L., Colaco C. B., Gharavi A. E., Elkon K. B., Loizou S., Hughes G. R. Thrombosis in systemic lupus erythematosus: striking association with the presence of circulating lupus anticoagulant. Br Med J (Clin Res Ed) 1983 Oct 8;287(6398):1021–1023. doi: 10.1136/bmj.287.6398.1021. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Boxer M., Ellman L., Carvalho A. The lupus anticoagulant. Arthritis Rheum. 1976 Nov-Dec;19(6):1244–1248. doi: 10.1002/art.1780190603. [DOI] [PubMed] [Google Scholar]
- Byron M. A. The clotting defect in SLE. Clin Rheum Dis. 1982 Apr;8(1):137–151. [PubMed] [Google Scholar]
- Carreras L. O., Defreyn G., Machin S. J., Vermylen J., Deman R., Spitz B., Van Assche A. Arterial thrombosis, intrauterine death and "lupus" antiocoagulant: detection of immunoglobulin interfering with prostacyclin formation. Lancet. 1981 Jan 31;1(8214):244–246. doi: 10.1016/s0140-6736(81)92087-0. [DOI] [PubMed] [Google Scholar]
- Carreras L. O., Vermylen J. G. "Lupus" anticoagulant and thrombosis--possible role of inhibition of prostacyclin formation. Thromb Haemost. 1982 Aug 24;48(1):38–40. [PubMed] [Google Scholar]
- Elias M., Eldor A. Thromboembolism in patients with the 'lupus'-type circulating anticoagulant. Arch Intern Med. 1984 Mar;144(3):510–515. [PubMed] [Google Scholar]
- Exner T., Rickard K. A., Kronenberg H. Studies on phospholipids in the action of a lupus coagulation inhibitor. Pathology. 1975 Oct;7(4):319–328. doi: 10.3109/00313027509081688. [DOI] [PubMed] [Google Scholar]
- Feinstein D. I., Rapaport S. I. Acquired inhibitors of blood coagulation. Prog Hemost Thromb. 1972;1:75–95. [PubMed] [Google Scholar]
- Jungers P., Liote F., Dautzenberg M. D., Gazengel C., Dougados M., Tron F., Bach J. F. Lupus anticoagulant and thrombosis in systemic lupus erythematosus. Lancet. 1984 Mar 10;1(8376):574–575. doi: 10.1016/s0140-6736(84)90982-6. [DOI] [PubMed] [Google Scholar]
- Lechner K. Acquired inhibitors in nonhemophilic patients. Haemostasis. 1974;3(2):65–93. doi: 10.1159/000214043. [DOI] [PubMed] [Google Scholar]
- Mueh J. R., Herbst K. D., Rapaport S. I. Thrombosis in patients with the lupus anticoagulant. Ann Intern Med. 1980 Feb;92(2 Pt 1):156–159. doi: 10.7326/0003-4819-92-2-156. [DOI] [PubMed] [Google Scholar]
- Pomeroy C., Knodell R. G., Swaim W. R., Arneson P., Mahowald M. L. Budd-Chiari syndrome in a patient with the lupus anticoagulant. Gastroenterology. 1984 Jan;86(1):158–161. [PubMed] [Google Scholar]
- Schleider M. A., Nachman R. L., Jaffe E. A., Coleman M. A clinical study of the lupus anticoagulant. Blood. 1976 Oct;48(4):499–509. [PubMed] [Google Scholar]
- Tan E. M., Cohen A. S., Fries J. F., Masi A. T., McShane D. J., Rothfield N. F., Schaller J. G., Talal N., Winchester R. J. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. 1982 Nov;25(11):1271–1277. doi: 10.1002/art.1780251101. [DOI] [PubMed] [Google Scholar]