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Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
. 1986 Jun;45(6):454–457. doi: 10.1136/ard.45.6.454

Improved method of isolating bacteria from joint fluids by the use of blood culture bottles.

R von Essen, A Hölttä
PMCID: PMC1001916  PMID: 3524479

Abstract

An analysis of 47 episodes of bacterial arthritis showed that applying a blood culture procedure to the culture of joint fluids gave positive results in 10 cases (21%) that were negative by conventional methods. When follow up samples taken during antibiotic treatment were considered the proportion of false negatives eliminated rose to 40%. The respective advantages of using a large volume of inoculum and a large volume of medium are that very low numbers of viable bacteria in infected fluid can be detected, and that growth inhibitors are diluted.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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