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. 1986 Dec;45(12):1019–1024. doi: 10.1136/ard.45.12.1019

Effects of dietary supplementation on autoimmunity in the MRL/lpr mouse: a preliminary investigation.

D G Godfrey, W H Stimson, J Watson, J F Belch, R D Sturrock
PMCID: PMC1002043  PMID: 3492970

Abstract

The effects of dietary fatty acid supplementation on various disease parameters in the spontaneously autoimmune MRL-mp-lpr/lpr mouse model of systemic lupus erythematosus before onset of disease were investigated. A fat deficient diet was supplemented with the following oils: olive oil, sunflower oil, evening primrose oil (EPO), fish oil, and a fish oil/EPO mixture. The mice receiving a diet enriched with EPO showed an increase in survival, as did those receiving the fish oil/EPO mixture. These results, taken together with those of the other parameters monitored, suggest that EPO may be of benefit in alleviating the murine form of the disease.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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