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. 1987 Apr;46(4):286–289. doi: 10.1136/ard.46.4.286

Prevalence of Sjögren's syndrome in autoimmune diseases.

J Coll, A Rives, M C Griñó, J Setoain, J Vivancos, A Balcells
PMCID: PMC1002121  PMID: 3592784

Abstract

Investigations were carried out in 122 patients in order to identify features of Sjögren's syndrome (keratoconjunctivitis sicca and xerostomia). There were 78 patients with autoimmune diseases (rheumatoid arthritis 21, scleroderma 16, sicca syndrome 16, primary biliary cirrhosis 14, and other autoimmune disorders 11), 11 patients with chronic liver disease other than primary biliary cirrhosis, and 33 patients with a variety of non-autoimmune conditions or no obvious disease. Keratoconjunctivitis sicca was diagnosed by Schirmer's test and rose bengal staining. The oral component was diagnosed by labial biopsy and salivary scintigraphy. Forty nine patients had a definite Sjögren's syndrome, and 77 patients had the syndrome definitely or probably. Definite Sjögren's syndrome occurred in 62% of patients with rheumatoid arthritis, in 69% of patients with scleroderma, and in 71% of patients with primary biliary cirrhosis. Sjögren's syndrome was not present in any of the patients with non-autoimmune conditions. These results show that in an unselected group of patients with Sjögren's syndrome the prevalence of rheumatoid arthritis (26%), scleroderma (22%), sicca syndrome (22%), and primary biliary cirrhosis (20%) is similar. Also the occurrence of Sjögren's syndrome in primary biliary cirrhosis is even higher than that in rheumatoid arthritis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Alarcón-Segovia D., Ibánez G., Hernández-Ortíz J., Velázquez-Forero F., González-Jiménez Y. Sjögren's syndrome in progressive systemic sclerosis (scleroderma). Am J Med. 1974 Jul;57(1):78–85. doi: 10.1016/0002-9343(74)90771-2. [DOI] [PubMed] [Google Scholar]
  2. BLOCH K. J., BUCHANAN W. W., WOHL M. J., BUNIM J. J. SJOEGREN'S SYNDROME. A CLINICAL, PATHOLOGICAL, AND SEROLOGICAL STUDY OF SIXTY-TWO CASES. Medicine (Baltimore) 1965 May;44:187–231. [PubMed] [Google Scholar]
  3. Chisholm D. M., Mason D. K. Labial salivary gland biopsy in Sjögren's disease. J Clin Pathol. 1968 Sep;21(5):656–660. doi: 10.1136/jcp.21.5.656. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Cipoletti J. F., Buckingham R. B., Barnes E. L., Peel R. L., Mahmood K., Cignetti F. E., Pierce J. M., Rabin B. S., Rodnan G. P. Sjögren's syndrome in progressive systemic sclerosis. Ann Intern Med. 1977 Nov;87(5):535–541. doi: 10.7326/0003-4819-87-5-535. [DOI] [PubMed] [Google Scholar]
  5. Drummond M. B., Montgomery R. D. Acute sprue in Britain. Br Med J. 1970 May 9;2(5705):340–341. doi: 10.1136/bmj.2.5705.340. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Kassan S. S., Thomas T. L., Moutsopoulos H. M., Hoover R., Kimberly R. P., Budman D. R., Costa J., Decker J. L., Chused T. M. Increased risk of lymphoma in sicca syndrome. Ann Intern Med. 1978 Dec;89(6):888–892. doi: 10.7326/0003-4819-89-6-888. [DOI] [PubMed] [Google Scholar]
  7. Moutsopoulos H. M., Chused T. M., Mann D. L., Klippel J. H., Fauci A. S., Frank M. M., Lawley T. J., Hamburger M. I. Sjögren's syndrome (Sicca syndrome): current issues. Ann Intern Med. 1980 Feb;92(2 Pt 1):212–226. doi: 10.7326/0003-4819-92-2-212. [DOI] [PubMed] [Google Scholar]
  8. Schall G. L., Anderson L. G., Wolf R. O., Herdt J. R., Tarpley T. M., Jr, Cummings N. A., Zeiger L. S., Talal N. Xerostomia in Sjögren's syndrome. Evaluation by sequential salivary scintigraphy. JAMA. 1971 Jun 28;216(13):2109–2116. [PubMed] [Google Scholar]
  9. Shearn M. A. Sjögren's syndrome. Semin Arthritis Rheum. 1972 Fall;2(2):165–190. doi: 10.1016/0049-0172(72)90008-x. [DOI] [PubMed] [Google Scholar]
  10. Simon L., Souyris F., Suquet P., Blotman F., Brami S., Lehn A., Rousse M. Les glandes salivaries au cours de la polyarthrite rhumatoïde. Rev Rhum Mal Osteoartic. 1976 Mar;43(3):185–192. [PubMed] [Google Scholar]
  11. VANSELOW N. A., DODSON V. N., ANGELL D. C., DUFF I. F. A clinical study of Sjogren's syndrome. Ann Intern Med. 1963 Jan;58:124–135. doi: 10.7326/0003-4819-58-1-124. [DOI] [PubMed] [Google Scholar]
  12. Whaley K., Goudie R. B., Williamson J., Nuki G., Dick W. C., Buchanan W. W. Liver disease in Sjögren's syndrome and rheumatoid arthritis. Lancet. 1970 Apr 25;1(7652):861–863. doi: 10.1016/s0140-6736(70)91690-9. [DOI] [PubMed] [Google Scholar]

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