Abstract
The potential use of magnetic resonance imaging (MRI) for inflammatory muscle disorders was evaluated in 13 patients with polymyositis and dermatomyositis. Abnormalities in signal intensity (p = 0.0076) and fat replacement (p = 0.0177) were identified and correlated significantly with clinical disease activity. In addition, MRI was useful in directing muscle biopsy of selected abnormal areas.
Full text
PDFImages in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Adams M. E., Li D. K. Magnetic resonance imaging in rheumatology. J Rheumatol. 1985 Dec;12(6):1038–1040. [PubMed] [Google Scholar]
- Baker D. G., Schumacher H. R., Jr, Wolf G. L. Nuclear magnetic resonance evaluation of synovial fluid and articular tissues. J Rheumatol. 1985 Dec;12(6):1062–1065. [PubMed] [Google Scholar]
- Bohan A., Peter J. B. Polymyositis and dermatomyositis (first of two parts). N Engl J Med. 1975 Feb 13;292(7):344–347. doi: 10.1056/NEJM197502132920706. [DOI] [PubMed] [Google Scholar]
- Borghi L., Savoldi F., Scelsi R., Villa M. Nuclear magnetic resonance response of protons in normal and pathological human muscles. Exp Neurol. 1983 Jul;81(1):89–96. doi: 10.1016/0014-4886(83)90159-0. [DOI] [PubMed] [Google Scholar]
- Calabrese L. H., Mitsumoto H., Chou S. M. Inclusion body myositis presenting as treatment-resistant polymyositis. Arthritis Rheum. 1987 Apr;30(4):397–403. doi: 10.1002/art.1780300406. [DOI] [PubMed] [Google Scholar]
- Edwards R. H., Griffiths R. D., Cady E. B. Topical magnetic resonance for the study of muscle metabolism in human myopathy. Clin Physiol. 1985 Apr;5(2):93–109. doi: 10.1111/j.1475-097x.1985.tb00586.x. [DOI] [PubMed] [Google Scholar]
- Murphy W. A., Totty W. G., Carroll J. E. MRI of normal and pathologic skeletal muscle. AJR Am J Roentgenol. 1986 Mar;146(3):565–574. doi: 10.2214/ajr.146.3.565. [DOI] [PubMed] [Google Scholar]
- Richardson M. L. Optimizing pulse sequences for magnetic resonance imaging of the musculoskeletal system. Radiol Clin North Am. 1986 Jun;24(2):137–144. [PubMed] [Google Scholar]